{"title":"Assessment of Antifungal Activity of Saccharomyces boulardii against Candida albicans Biofilm","authors":"Z. Sadeghi Ardestani, M. Yadegari, R. Kachuei","doi":"10.52547/iem.8.3.243","DOIUrl":null,"url":null,"abstract":") and MTT reduction reaction. The collected data were analyzed using student’s t-test in SPSS statistical software. Findings: In this study, the probiotic yeast S. boulardii reduced the pathogenicity and virulence of C. albicans in vitro. According to the results of CVS and MTT assays, a considerable reduction ( p < .001) in the biomass and viability of C. albicans biofilms was observed after 48 hours of incubation in the presence of S. boulardii extract. Conclusion: There was a significant association between S. boulardii extract concentration and biofilm formation in both CVS and MTT assays. Biofilm formation decreased with increasing S. boulardii extract concentration and incubation time in both methods compared to the control group .","PeriodicalId":34545,"journal":{"name":"Infection Epidemiology and Microbiology","volume":"113 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Infection Epidemiology and Microbiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.52547/iem.8.3.243","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
) and MTT reduction reaction. The collected data were analyzed using student’s t-test in SPSS statistical software. Findings: In this study, the probiotic yeast S. boulardii reduced the pathogenicity and virulence of C. albicans in vitro. According to the results of CVS and MTT assays, a considerable reduction ( p < .001) in the biomass and viability of C. albicans biofilms was observed after 48 hours of incubation in the presence of S. boulardii extract. Conclusion: There was a significant association between S. boulardii extract concentration and biofilm formation in both CVS and MTT assays. Biofilm formation decreased with increasing S. boulardii extract concentration and incubation time in both methods compared to the control group .
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