The application of metagenomics in hydrocarbon resource management

M. Gana, J. Kure, U. Ahmadu
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Abstract

The last 5-10 years has witness a new proven field of research where explanation have been provided to non-cultured microbes. This uncultured microorganisms forms the major group of organisms found in most environment of the Earth. The science of metagenomics makes it possible to investigate resources which can be used to develop new enzymes, genes and several chemical compounds for use in biotechnology. Studies of microorganisms in pure laboratory culture for over a century have led to significant advances into microbial genetics and physiology, biotechnology and molecular biology. The rapid advancement in sequencing technology has brought about drastic reduction cost of sequencing thereby leading to increasing sequencing project been undertaken. This advancement has provided the privilege for the continual use of this sequencing technology to monitor microbes in the environment which before now are not available. While metagenomic applications have been used to consistently have a better understanding of ecology and microbial diversity, it is pertinent to note that its application in environmental monitoring and application is commonly increasing and has been one of the research areas in focus. To this end this article seek to provide a general overview of what metagenmics is, its principle and application in hydrocarbon resource management.
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宏基因组学在油气资源管理中的应用
过去的5-10年见证了一个新的研究领域,其中解释了非培养微生物。这种未经培养的微生物构成了地球上大多数环境中发现的主要生物群。宏基因组学使研究资源成为可能,这些资源可用于开发用于生物技术的新酶、基因和几种化合物。一个多世纪以来,对纯实验室培养微生物的研究在微生物遗传学和生理学、生物技术和分子生物学方面取得了重大进展。随着测序技术的飞速发展,测序成本大幅降低,测序项目也随之增多。这一进步为持续使用这种测序技术来监测环境中的微生物提供了特权,这在以前是不可用的。虽然宏基因组的应用一直被用来更好地了解生态和微生物多样性,但值得注意的是,它在环境监测和应用中的应用正在普遍增加,并已成为重点研究领域之一。为此,本文试图对何谓宏生学、宏生学原理及其在油气资源管理中的应用作一概述。
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