Phytosolutions for Enterococcus faecalis in Endodontics: An Update

Al-Moosawi As, S. Bedi, K. Almas
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引用次数: 7

Abstract

Background: The key reason for failure of an endodontic treatment is incomplete debridement and sterilization because of complex root canal system anatomy which makes elimination of micro-organisms difficult. In spite of the chemical and mechanical debridement of root canals, studies have reported that some microbes like Enterococcus faecalis thrive in periapical lesions, triggering a failure of an endodontic treatment. Considering the vanity, adverse effects and toxicity issues of synthetic medications, the herbal alternatives have been sought for endodontic irrigation. Objectives: To review the current evidence on the efficacy of different plant derivatives against Enterococcus faecalis. Materials and methods: Studies were identified through systematic search of the following electronic databases: PubMed, Web of Science, Scopus, Google Scholar and Cochrane database of systematic reviews. The results from the relevant published literatures are discussed. Summary and Conclusion: The conclusion drawn from in vitro and in vivo studies seems encouraging and as proven in clinical studies, Propolis and Salvadora persica have been proven to be efficacious against Enterococcus faecalis. More laboratory and clinical research is required to assess the safety, efficacy and biocompatibility of other plant extracts, before finally recommending them as alternative endodontic irrigants.
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牙髓学中粪肠球菌的植物溶液:最新进展
背景:根管系统解剖结构复杂,微生物清除困难,导致根管治疗失败的主要原因是清创术和灭菌不彻底。尽管对根管进行化学和机械清创,但有研究报道,一些微生物,如粪肠球菌,在根尖周围病变中大量繁殖,导致根管治疗失败。考虑到合成药物的虚荣度、不良反应和毒性问题,人们一直在寻求草药替代品来进行牙髓冲洗。目的:综述不同植物衍生物抗粪肠球菌作用的研究进展。材料和方法:通过系统检索以下电子数据库:PubMed、Web of Science、Scopus、Google Scholar和Cochrane系统综述数据库来确定研究。讨论了相关已发表文献的结果。摘要与结论:体外和体内研究得出的结论令人鼓舞,并且在临床研究中证实蜂胶和木耳对粪肠球菌有效。需要更多的实验室和临床研究来评估其他植物提取物的安全性、有效性和生物相容性,然后才最终推荐它们作为替代的牙髓冲洗剂。
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