ACUTE KIDNEY INJURY IN PATIENTS WITH ACUTE LEUKEMIA AFTER HEMATOPOIETIC STEM CELL TRANSPLANTATION: A SERIES OF CLINICAL CASES

Oncologia i radiologia Kazakhstana Pub Date : 2022-09-30 DOI:10.52532/2663-4864-2022-3-65-32-36

A. Murzakhmetova, V. Kemaikin, A. Ainabay, A. Meiramova, B. Ainabekova

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Abstract

Relevance: Acute renal kidney injury is a severe complication in patients with acute leukemia who underwent hematopoietic stem cell transplantation (HSCT). According to statistics, acute renal dysfunction often occurs in the first 100 days after HSCT. This study aimed to evaluate kidney function in patients with acute leukemia after hematopoietic stem cell transplantation. Methods: The article presents clinical cases of patients with acute lymphoblastic leukemia who developed acute renal failure after HSCT. The dynamics of the functional state of kidneys in patients with acute lymphoblastic leukemia after HSCT are described. Results: The acute kidney disorder in the studied patients was mainly caused by HSCT complications. We have identified renal kidney damage in the form of acute tumor lysis and thrombotic microangiopathy. Conclusion: Patients with acute lymphoblastic leukemia risk developing acute kidney disorder during HSCT, which requires careful monitoring of kidney function, especially in the early post-transplant period

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急性白血病患者造血干细胞移植后急性肾损伤:一系列临床病例

相关性:急性肾损伤是急性白血病患者接受造血干细胞移植(HSCT)的严重并发症。据统计，急性肾功能障碍常发生在移植后的前100天。本研究旨在评估急性白血病患者造血干细胞移植后的肾功能。方法:本文报道急性淋巴细胞白血病患者造血干细胞移植后并发急性肾功能衰竭的临床病例。急性淋巴细胞白血病患者肾移植后肾功能状态的动态描述。结果:研究患者的急性肾脏疾病主要由移植并发症引起。我们已经确定肾肾损害的形式急性肿瘤溶解和血栓性微血管病。结论:急性淋巴细胞白血病患者在造血干细胞移植过程中有发生急性肾脏疾病的风险，需要仔细监测肾功能，尤其是移植后早期

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Oncologia i radiologia Kazakhstana

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