Herminia Castán Urbano, Mª. Adolfina Ruiz Martínez, M. Rodriguez, Elena Ortega Martínez y, M. E. M. Hernández
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Abstract
Melatonin is a hormone with multiple actions, one of which, with proper administration, is the ability to control weight and prevent cardiovascular illnesses associated with obesity and diabetes. So, this work focuses on the design and creation of bilayer tablets which, through the top layer, permit a faster melatonin release after administration and, through the other layer, offer an extended release over time. The tablets are characterized from a technological perspective and have been subjected to disintegration and release tests to help determine their biopharmaceutical profile.
期刊介绍：
Primary Health Care Research & Development is aimed specifically at both researchers and practitioners in primary health care, bridging the gap between the two areas. It provides a forum for the publication of international, interdisciplinary research and development in primary health care. It is essential reading for all involved in primary care: nurse practitioners, GPs and health service managers; professional and local groups in community health; researchers and academics; purchasers of primary health care services; allied health practitioners in secondary services and health-related consumer groups.
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