The analysis of the effectiveness and safety of levofloxacin in the treatment of lower respiratory tract infection.

International Current Pharmaceutical Journal Pub Date : 2015-11-07 DOI:10.3329/ICPJ.V4I12.25598

Ibrahim Alreshidi, Khalid M. Al-Mutairi, Xie Han

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Abstract

Objective of the current study was to investigate the effectiveness and safety of levofloxacin in the treatment of lower respiratory tract infection. The study was carried out in hospital on 120 patients with lower respiratory tract infection from January 2014 to January 2015. Patients were randomly divided into control and observation groups, each group contained 60 patients. The control group was given the routine dose of levofloxacin, whereas the observation group received the high dose of levofloxacin. The clinical effectiveness and incidence rate of untoward reactions between the two groups were statistically analyzed and evaluated. Patients’ cure rate in the observation group was 53.33%, significantly higher than that of the control group which was only 36.67%. Their differences have statistical significance (P 0.05). This study shows better clinical curative effect of high doses of levofloxacin treating lower respiratory infection with minimum risk. This method, which can significantly improve the quality of patient treatment with low adverse reaction risk, is worth popularizing in clinical use. Alreshidi et al., International Current Pharmaceutical Journal, November 2015, 4(12): 462-464

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左氧氟沙星治疗下呼吸道感染的有效性和安全性分析。

本研究旨在探讨左氧氟沙星治疗下呼吸道感染的有效性和安全性。对2014年1月至2015年1月住院的120例下呼吸道感染患者进行研究。将患者随机分为对照组和观察组，每组60例。对照组给予常规剂量左氧氟沙星治疗，观察组给予大剂量左氧氟沙星治疗。对两组患者的临床疗效及不良反应发生率进行统计分析和评价。观察组患者治愈率为53.33%，显著高于对照组的36.67%。差异有统计学意义(p0.05)。本研究显示，大剂量左氧氟沙星治疗下呼吸道感染的临床疗效较好，且风险最小。该方法可显著提高患者治疗质量，不良反应风险低，值得在临床推广使用。Alreshidi等，国际药学杂志，2015,4(12):462-464

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International Current Pharmaceutical Journal

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