Modern possibilities of diagnosis of cell’s membrane-receptor complex dysfunction in the acute period of ischemic stroke

Abstract

– patients with severe IS (average score on the NIHSS scale 24.06±0.29). Results. In the control group, there was a significant decrease after exposure to adrenaline solution. The reaction to adrenaline in patients with IS was almost absent. It indicates a decreasing of erythrocytes β-adrenoceptors (β-ARs) sensitivity to stimulants due to their desensitisation. In patients with moderate severity, erythrocytes are more reactive than in patients with more severe IS. erythrocytes a of a specific response of cells to biologically active substances and depends on the functional of the sympathoad renal system