Synthesis of Ibuprofen Using Silica-Supported Preyssler Nanoparticles as an Eco-Friendly, Inexpensive, and Efficient Catalyst

A. Gharib, N. Pesyan, L. V. Fard, M. Roshani
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引用次数: 6

Abstract

This paper describes an alternative and simple procedure for the synthesis of Ibuprofen using Silica-Supported Preyssler Nanoparticles (H14[NaP5W30O110]/SiO2) (SPNPs), as an eco-friendly, inexpensive, and efficient catalyst. High yields, simplicity of operation, and easy work-up procedure are some advantages of this protocol. Silica-Supported Preyssler Nanoparticles (H14[NaP5W30O110]/SiO2) (SPNPs) offer the advantages of a higher hydrolytic and thermal stability. The salient features of Preyssler’s anion are availability, nontoxicity and reusability. We believe this methodology can find usefulness in organic synthesis.
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二氧化硅负载的Preyssler纳米颗粒作为环保、廉价、高效的催化剂合成布洛芬
本文介绍了一种替代的、简单的合成布洛芬的方法,该方法使用二氧化硅负载的Preyssler纳米颗粒(H14[NaP5W30O110]/SiO2) (SPNPs)作为一种环保、廉价、高效的催化剂。该方法收率高,操作简单,易于操作。二氧化硅负载的Preyssler纳米颗粒(H14[NaP5W30O110]/SiO2) (SPNPs)具有较高的水解稳定性和热稳定性。普雷斯勒阴离子的显著特点是可用性、无毒性和可重复使用。我们相信这种方法在有机合成中是有用的。
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