Cytological Findings in Testicular FNAC in Azoospermia Patient: A Study of 395 Cases

Md. Saiful Islam, Papri Dutta, N. Dey, M. Kabir
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Abstract

Background: In the age of assisted reproduction, search for the cause of male infertility is increasing in numbers. As finding of obstructive azoospermia give the male a hope there are increased requisition to the cytopathologist to evaluate the spermatogenesis status of a male. The aim of the study was to see the cytomorphological pattern in azoospermia patients and to determine the procedure's safety. Materials and methods:    From January 2015 to June 2022, in Chattogram, Bangladesh, 395 patients with azoospermia were taken in this descriptive study. After all aseptic precautions and local anesthetization aspiration was done from both testes. Cytomorphological analysis was done in the following classes i) Positive for spermatogenesis ii) Hypo-spermatogenesis iii) Early maturation arrest iv) Late maturation arrest v) Sertoli cell only vi) Atrophic. Results: Cytological diagnosis yielded 161 (40.76%) positive for spermatogenesis, indicating obstructive azoospermia, seconded by 'Sertoli cell only' in 115 (29.11%) patients. Both conditions were highest in the age group of 31-40, 93(57.76%) and 72 (62.6%). Hematoma was seen in 04(1.01%) cases and extended period of pain was experienced by 05 (1.26%) patients. Conclusion: FNA of the testis is a much simpler and easily accessible procedure to assess the spermatogenesis status of an azoospermia patient. Chatt Maa Shi Hosp Med Coll J; Vol.22 (1); January 2023; Page 53-56
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无精子症患者睾丸FNAC的细胞学表现:附395例研究
背景:在辅助生殖时代,对男性不育原因的研究越来越多。由于发现阻塞性无精子症给男性带来了希望,因此对细胞病理学家评估男性精子发生状况的要求越来越高。该研究的目的是观察无精子症患者的细胞形态学模式,并确定该手术的安全性。材料与方法:2015年1月至2022年6月,在孟加拉国Chattogram,选取395例无精子症患者进行描述性研究。所有无菌注意事项及局部麻醉后,双睾丸穿刺。细胞形态学分析分为以下几类:1)生精阳性2)生精不足3)早熟阻滞4)晚成熟阻滞5)仅支持细胞6)萎缩。结果:细胞学诊断为161例(40.76%)患者精子发生阳性,提示阻塞性无精子症,其次为115例(29.11%)患者仅为支持细胞。31 ~ 40岁以93岁(57.76%)和72岁(62.6%)最高。血肿04例(1.01%),长时间疼痛05例(1.26%)。结论:睾丸FNA是评估无精子症患者精子发生状况的一种简单易行的方法。上海医科大学医学院;工程系(1);2023年1月;页面53-56
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