Mussel adhesive proteins as surgical sealants in post-extraction: Literature review

Haswamati Hasan, Ramadhan Alfitrah Syamsir Dewang
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Abstract

Background and objective: Tooth extraction is a dental procedure of removing a tooth from its socket, causing an injury. Dental socket wounds that are directlyexposed to the oral environment allow the entry of pathogenic micro-organisms that can cause post-extraction bleeding, alveolar osteitis, oroantral fistula, and others. Recent studies have shown that the use of mussel adhe-sive proteins (MAPs) without sutures or staples can accelerate socket wound closure or stopbleeding after tooth extraction. Con-clusion: MAPs that have been synthesized into injectable citrate-based mussel-inspired bioadhesive have the potential assurgical sealants after tooth extraction because they have strong adhesive properties in wet environments, good esthetics, atraumatic, and short operating time.
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贻贝黏附蛋白在拔牙后外科密封中的应用:文献综述
背景和目的:拔牙是一种将牙齿从牙槽中取出并造成损伤的牙科手术。直接暴露于口腔环境的牙槽口伤口允许病原微生物进入,可引起拔牙后出血、牙槽骨炎、口窦瘘等。最近的研究表明,使用贻贝黏附蛋白(MAPs)而不使用缝合线或钉可以加速牙槽口伤口愈合或在拔牙后止血。结论:将MAPs合成为可注射型柠檬酸盐基贻贝生物胶粘剂,具有湿润环境下粘接性能强、美观性好、无创伤性好、手术时间短等优点,具有拔牙后外科密封的潜力。
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