{"title":"Bubble generation in microfluidic devices","authors":"C. Martinez","doi":"10.1179/175889709X446561","DOIUrl":null,"url":null,"abstract":"AbstractMicrofluidics has provided a rapid and inexpensive prototyping tool for the exploration and manipulation of multiphase flow at low Reynolds numbers. This has opened up a new realm of possibilities regarding the compartmentalisation of fluids via the generation of monodispersed drops and bubbles. Bubble formation is an area of growing interest in the microfluidic community and the aim of this article is to review the latest advances in bubble generation in microfluidic devices. The review starts with a full description of axisymmetric and asymmetric flow focusing devices. Details on the mechanism of bubble formation and the dependence of bubble size as a function of gas and liquid flow rates are provided. T junction and parallel channel bubble generators are also discussed and compared to the other flow focusing configurations. The last section provides an overview of different applications of bubbles in microfluidic channels.","PeriodicalId":88410,"journal":{"name":"Bubble science engineering and technology","volume":"120 1","pages":"40-52"},"PeriodicalIF":0.0000,"publicationDate":"2009-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"24","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bubble science engineering and technology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1179/175889709X446561","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 24
Abstract
AbstractMicrofluidics has provided a rapid and inexpensive prototyping tool for the exploration and manipulation of multiphase flow at low Reynolds numbers. This has opened up a new realm of possibilities regarding the compartmentalisation of fluids via the generation of monodispersed drops and bubbles. Bubble formation is an area of growing interest in the microfluidic community and the aim of this article is to review the latest advances in bubble generation in microfluidic devices. The review starts with a full description of axisymmetric and asymmetric flow focusing devices. Details on the mechanism of bubble formation and the dependence of bubble size as a function of gas and liquid flow rates are provided. T junction and parallel channel bubble generators are also discussed and compared to the other flow focusing configurations. The last section provides an overview of different applications of bubbles in microfluidic channels.
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