S. G. Petrosyan, L. Sahakyan, V. Kirakosyan, Ella V. Minasyan, Siranush Ye. Sardaryan
{"title":"ISOLATION, IDENTIFICATION AND QUANTITATIVE DETERMINATION OF NIFEDIPINE FROM BIOLOGICAL MATERIAL","authors":"S. G. Petrosyan, L. Sahakyan, V. Kirakosyan, Ella V. Minasyan, Siranush Ye. Sardaryan","doi":"10.46991/pysu:b/2021.55.3.204","DOIUrl":null,"url":null,"abstract":"The optimal conditions of the method, applicable during forensic chemical examinations, were elaborated. Particularly, the investigation of the conditions for the isolation of Nifedipine from liver and skeletal muscle tissues, the identification of the isolated Nifedipine by TLC method and checking the accuracy of the method using HPLC was carried out. As a result, a new alternative express method for the isolation and further identification of Nifedipine from different biomaterials was elaborated. The method is quite fast, accurate and much cheaper.","PeriodicalId":20692,"journal":{"name":"Proceedings of the YSU B: Chemical and Biological Sciences","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the YSU B: Chemical and Biological Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.46991/pysu:b/2021.55.3.204","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The optimal conditions of the method, applicable during forensic chemical examinations, were elaborated. Particularly, the investigation of the conditions for the isolation of Nifedipine from liver and skeletal muscle tissues, the identification of the isolated Nifedipine by TLC method and checking the accuracy of the method using HPLC was carried out. As a result, a new alternative express method for the isolation and further identification of Nifedipine from different biomaterials was elaborated. The method is quite fast, accurate and much cheaper.
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