KEMAMPUAN EKSTRAK SEKUENSIAL DAGING BUAH PALA SEBAGAI AGEN HIPOGLIKEMIK UNTUK PENYERAPAN GLUKOSA

IF 1 4区化学 Q4 CHEMISTRY, MULTIDISCIPLINARY 化学进展 Pub Date : 2021-11-30 DOI:10.35799/cp.14.2.2021.37114

Auliya Rizky Harjono Paijo, Rebecca Teisha Indriawan, Marsel Refanli Karisoh, Adinda Putri Maharani Susmantoyo, E. Suryanto, M. Runtuwene

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Abstract

Diabetes adalah salah satu penyakit kronis yang paling umum terjadi pada manusia, yang ditandai dengan kekurangan insulin yang menyebabkan peningkatan glukosa darah secara terus-menerus serta perubahan metabolisme lipid dan protein. Beberapa penelitian telah melaporkan bahwa buah pala (Myristica fragrans Houtt.) menunjukkan beberapa aktivitas yaitu sitotoksik, hepatoprotektif, antioksidan, antiinflamasi, antitrombotik, hipolipidemia, antiaterosklerotik, hipoglisemik dan antidiabetik. Tujuan penelitian ini adalah untuk mengetahui potensi dari ekstrak daging buah pala sebagai agen hipoglisemik. Penelitian ini dilakukan secara in vitro. Hasil yang diperoleh menunjukkan bahwa ekstrak daging buah pala dapat digunakan sebagai agen hipoglisemik. ABSTRACT Diabetes is one of the most common chronic diseases in humans, which is characterized by insulin deficiency which causes persistently elevated blood glucose and changes in lipid and protein metabolism. Several studies have reported that nutmeg exhibits several activities, namely cytotoxic, hepatoprotective, antioxidant, anti-inflammatory, antithrombotic, hypolipidemic, antiatherosclerotic, hypoglycemic and antidiabetic. The purpose of this study was to determine the potential of nutmeg pulp extract as a hypoglycemic agent. The method used in this research is in vitro testing. The results obtained indicate that the extract of nutmeg pulp can be used as a hypoglycemic agent.

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肉豆蔻以低血糖剂吸收葡萄糖的能力

糖尿病是人类最常见的慢性疾病之一，其特点是胰岛素缺乏，导致血糖持续升高，脂质和蛋白质代谢发生变化。一些研究报告称，肉豆蔻(Myristica fragrans Houtt)表现为sitotoksik、hepatoc保护、抗氧化剂、抗氧化、消炎药、抗血性、抗淀粉性、动脉粥样硬化、低血糖和抗糖尿病的多种活动。本研究的目的是确定肉豆蔻提取物作为低血糖剂的潜力。这项研究是在体外进行的。结果表明，肉豆蔻提取物可以用作低血糖剂。糖尿病是人类最常见的疾病之一，其特点是血液葡萄糖和代谢蛋白不断升高和变化。Several studies报告说，有疯狂的活动，namely cytoxic, hepatoxic，抗疟，抗炎性，抗血性，抗血液学，抗血液学，抗血液学，抗血液学，抗血液学，这项研究的目的是确定坚果纸浆作为低血糖剂的潜在存在。这项研究使用的方法是体外试验。被证实的证据表明，疯子的纸浆被用作低血糖剂。

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来源期刊

化学进展化学-化学综合

CiteScore

2.10

自引率

15.40%

发文量

4325

审稿时长

2.5 months

期刊介绍： Progress in Chemistry is a peer-reviewed monthly journal. It is sponsored by the Chinese Academy of Sciences(CAS) and the National Natural Science Foundation of China(NSFC). It provides a forum to publish review papers of specialized topics covering the full spectrum of chemistry in Chinese or English, with emphasis on those topics of emerging research area. The reviews provide comprehensive information, including recent advances, development trends, as well as critical assessments about the subject. The readers interested are : researchers and students in chemistry and related areas, and policy decision-makers. Most members of the editorial board are famous scientists.