Formulation and evaluation of oxymel containing fenugreek extract

Deepa Sarvan Mudaliyar, Sanika Datta Chavan, Soni Ashok Kushwaha, Rudra prasadrao Eppili, Shivani Bharat Khaladkar, Shriniwas Pramod Patil
{"title":"Formulation and evaluation of oxymel containing fenugreek extract","authors":"Deepa Sarvan Mudaliyar, Sanika Datta Chavan, Soni Ashok Kushwaha, Rudra prasadrao Eppili, Shivani Bharat Khaladkar, Shriniwas Pramod Patil","doi":"10.53771/ijlsra.2023.4.2.0061","DOIUrl":null,"url":null,"abstract":"Introduction: Trigonella foenum-graecum is medicinal plant of family Fabaceae, consists of bitter principles and traditionally used in treatment of diabetes and hepatoprotective. To mask its bitter taste, it could be formulated in honey based oral formulations like oxymel. Honey, as a saturated solution of various sugars, as per Ayurvedic system of medicine, could be consumed along with drug. This research attempt was aimed towards aqueous extraction of fenugreek seeds; formulation of oxymel by addition to honey and evaluation for different parameters. Oxymel was formulated as per procedure mentioned in United State Pharmacopeia for squill oxymel; and evaluated for pharmaceutical parameters those applied for oral syrups. Results: The oxymel formulated was pale brownish with agreeable odour and sweet taste. It was pourable with viscosity of 80 CP measured at 100 rpm while density was found to be 1.47 g/cm³. There was also ease in cap opening of its container, also no crystallization of honey was observed. Its trigonelline content was found to be 3.6 µg/ml. Conclusion: Alkaloids of fenugreek have significant pharmacological activities in human being, if administered orally. To mask their bitter taste and facilitate their increase in absorption, Trigonella foenum-graecum can successfully be formulated in honey based oral formulation of oxymel.","PeriodicalId":14144,"journal":{"name":"International Journal of Life Science Research Archive","volume":"71 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Life Science Research Archive","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.53771/ijlsra.2023.4.2.0061","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Introduction: Trigonella foenum-graecum is medicinal plant of family Fabaceae, consists of bitter principles and traditionally used in treatment of diabetes and hepatoprotective. To mask its bitter taste, it could be formulated in honey based oral formulations like oxymel. Honey, as a saturated solution of various sugars, as per Ayurvedic system of medicine, could be consumed along with drug. This research attempt was aimed towards aqueous extraction of fenugreek seeds; formulation of oxymel by addition to honey and evaluation for different parameters. Oxymel was formulated as per procedure mentioned in United State Pharmacopeia for squill oxymel; and evaluated for pharmaceutical parameters those applied for oral syrups. Results: The oxymel formulated was pale brownish with agreeable odour and sweet taste. It was pourable with viscosity of 80 CP measured at 100 rpm while density was found to be 1.47 g/cm³. There was also ease in cap opening of its container, also no crystallization of honey was observed. Its trigonelline content was found to be 3.6 µg/ml. Conclusion: Alkaloids of fenugreek have significant pharmacological activities in human being, if administered orally. To mask their bitter taste and facilitate their increase in absorption, Trigonella foenum-graecum can successfully be formulated in honey based oral formulation of oxymel.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
含胡芦巴提取物氧梅尔的配方及评价
简介:三角Trigonella foenum-graecum是豆科药用植物,由苦原理组成,传统上用于治疗糖尿病和保肝。为了掩盖它的苦味,它可以被制成以蜂蜜为基础的口服配方,比如oxymel。根据阿育吠陀医学体系,蜂蜜是各种糖的饱和溶液,可以和药物一起服用。本研究旨在对胡芦巴种子进行水提;蜂蜜加氧梅尔的配方及不同参数的评价。Oxymel按照美国药典中提到的程序配制。并对用于口服糖浆的药物参数进行了评价。结果:该制剂为淡棕色,气味宜人,口感甘甜。浇注时粘度为80 CP,转速为100 rpm,密度为1.47 g/cm³。在其容器的盖子打开也很容易,也没有观察到蜂蜜的结晶。其葫芦巴碱含量为3.6µg/ml。结论:胡芦巴生物碱具有显著的药理活性。为了掩盖它们的苦味并促进它们的吸收,可以成功地在蜂蜜为基础的口服oxymel配方中配制茴香草。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Assessment of the effects of physiological development of cocoa (Theobroma cacao l.) explant on somatic embryogenesis Tinea capitis due to Microsporum canis in the ‎university hospital Hassan II of fez: ‎Epidemiological and mycological ‎profile The challenges of installing Picture Archiving and Communication Systems (PACS) in a low- or poor-income resource nation: Our experience in a teaching hospital in Sub-Saharan Africa Utilization of maggot (Heermetia illucens) as raw material for feed on the physical quality of fish feed Classical and molecular detection methods in aquatic environmental virology for waterborne diseases outbreaks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1