The Use of Salivary Gland Scintigraphy for Diagnosis of Primary Sjögren Syndrome and Thyroid Disease in Patients with Dry Mouth

Keun jeong Park, B. Kim, Jung Eun Lee, Younjung Park, J. Kwon, Hyung-Joon Ahn, Jong-hoon Choi
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Abstract

Received November 28, 2019 Revised December 10, 2019 Accepted December 10, 2019 Sjögren syndrome (SS) is a chronic autoimmune disease characterized by dryness of the mouth and eyes due to lymphocytic infiltration of the exocrine glands. In American European Consensus Group (AECG) criteria, abnormal salivary gland scintigraphy (SGS) result is one of the objective signs of SS and it has been proposed as a valid and non-invasive alternative approach to functional evaluation of salivary gland, especially in the case when unstimulated whole salivary flow is more than 1.5 mL in 15 minutes or other AECG criteria is unmet. Patients with SS are more likely to have the thyroid disease (TD), but this association remains controversial. We present a case of the use of SGS for diagnosis of primary SS and TD in patients with dry mouth and burning sensation of tongue. Through this case, we suggest the usefulness of salivary scintigraphy for screening TD in addition to diagnosis of SS.
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涎腺闪烁显像在口干患者原发性Sjögren综合征和甲状腺疾病诊断中的应用
Sjögren综合征(SS)是一种慢性自身免疫性疾病,以外分泌腺淋巴细胞浸润引起的口腔和眼睛干燥为特征。在AECG (American European Consensus Group)标准中,唾液腺scintigraphy (SGS)结果异常是SS的客观标志之一,被认为是一种有效的、无创的唾液腺功能评估的替代方法,特别是当非刺激的全唾液流量在15分钟内超过1.5 mL或不符合其他AECG标准时。SS患者更容易发生甲状腺疾病(TD),但这种关联仍存在争议。我们提出一个病例使用SGS诊断原发性SS和TD患者口干和舌烧灼感。通过这个病例,我们建议除了诊断SS外,唾液扫描还可以用于筛查TD。
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