Review of Anaesthesia and Analgesia in Patients with COVID-19 in Brazil

Monica Melo, Júlia Ferreira Nogueira, Lucas Vinicius Andrade dos Santos, Luis Sousa, Raiane Nascimento Santana, Weslly Jonas Severo da Silva, Wictor Hugo de Souza Silva, Makson G. B. Oliveira
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引用次数: 1

Abstract

Severe acute respiratory syndrome (COVID-19), produced by SARS-CoV-2, remains a challenge for modern medicine and a global health problem. For every 100 patients with COVID-19, about 20 need hospital care. In addition, some patients will be intubated and others under mechanical ventilation. Therefore, it is necessary to use drugs as a sedative and analgesic purpose, mainly. Thus, this study brings a survey on the drugs that can be used for the management of patients with COVID-19 in cases of intubation and mechanical ventilation in Brazil. In this paper, we will report the classes of anaesthetic and analgesic drugs. Highlighting the clinical indications for use, pharmacological characteristics of each drug in terms of doses, pharmacokinetics, pharmacodynamics and possible side effects and, in addition, peculiarities of drugs related to use in patients with COVID-19, when possible.
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巴西COVID-19患者麻醉和镇痛研究综述
由SARS-CoV-2引起的严重急性呼吸系统综合征(COVID-19)仍然是现代医学面临的挑战和全球卫生问题。每100名COVID-19患者中,约有20人需要住院治疗。此外,一些患者将插管,另一些患者将采用机械通气。因此,有必要使用以镇静和镇痛为主要目的的药物。因此,本研究对巴西在插管和机械通气病例中可用于管理COVID-19患者的药物进行了调查。在本文中,我们将报告麻醉和镇痛药物的类别。尽可能强调临床适应症、每种药物在剂量、药代动力学、药效学和可能的副作用方面的药理学特征,以及与COVID-19患者使用相关的药物的特点。
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