Н. Н. Мурашкин, Э. Т. Амбарчян, А. И. Материкин, Р. В. Епишев
{"title":"Роль нарушений эпидермального барьера при атопическом дерматите: современные концепции патогенеза заболевания","authors":"Н. Н. Мурашкин, Э. Т. Амбарчян, А. И. Материкин, Р. В. Епишев","doi":"10.15690/VSP.V17I1.1859","DOIUrl":null,"url":null,"abstract":"Atopic dermatitis is a common chronic inflammatory skin disease characterized by a recurring course and progressive decrease in the quality of life. Recent studies in this area demonstrate the multifaceted pathogenesis of atopic dermatitis. Interaction of such factors as epidermal dysfunction, immune system disorders, and the consequences of genetic mutations contributes not only to the development of the disease but also to its progression and chronic course. The article presents various components of the etiopathogenesis of atopic dermatitis, describes the role of lipids, thereby the new therapeutic targets are revealed to specialists.","PeriodicalId":10919,"journal":{"name":"Current Paediatrics","volume":"4 1","pages":"85-88"},"PeriodicalIF":0.0000,"publicationDate":"2018-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"7","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Paediatrics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15690/VSP.V17I1.1859","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 7
Abstract
Atopic dermatitis is a common chronic inflammatory skin disease characterized by a recurring course and progressive decrease in the quality of life. Recent studies in this area demonstrate the multifaceted pathogenesis of atopic dermatitis. Interaction of such factors as epidermal dysfunction, immune system disorders, and the consequences of genetic mutations contributes not only to the development of the disease but also to its progression and chronic course. The article presents various components of the etiopathogenesis of atopic dermatitis, describes the role of lipids, thereby the new therapeutic targets are revealed to specialists.
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