Association between Gallstone Disease and Metabolic Syndrome.

Abstract

introduction: Gallbladder stone disease is common and a leading cause of inpatient admissions for gastro-intestinal problem in modern world. Metabolic syndrome is slowly assuming shape of a global epidemic. There is currently only minimal data regarding the relationship between cholelithiasis and Metabolic syndrome in Indians. This study aims to assess if there is an association between the presence of gallstones and Metabolic Syndrome. Material and methods: At a tertiary care centre in Mumbai, 100 patients with cholelithiasis were compared with 100 controls to assess the profile with respect to Metabolic Syndrome. Result: 36% cases had Metabolic syndrome as against 16% controls. Of the components of Metabolic syndrome, obesity was the only one found to have a positive association. Conclusion: In our study, gallstone disease showed a statistically significant association with metabolic syndrome, however this association was positive only in female patients.