Biljana M Šmit, P. Stanić, Marijana Zivkovic, Z. Ratković, Jovana Muskinja
{"title":"Thiohydantoins from vanillin and its derivatives - Synthesis and Characterization","authors":"Biljana M Šmit, P. Stanić, Marijana Zivkovic, Z. Ratković, Jovana Muskinja","doi":"10.3390/ecsoc-23-06656","DOIUrl":null,"url":null,"abstract":"Hydantoins and their sulfur containing analogues, thiohydantoins, are an important and interesting moiety. They represent a big group of structurally diverse compounds with intriguing physical, chemical and biological properties, which enabled them to be used in therapy, medicine in general, material science and industry. With the goal of broadening the set of potentially applicable hydantoin derivatives, we have synthesized a series of 2-thiohydantoins from vanillin and its derivatives, which themselves posses interesting biological properties. All compounds were fully characterized by NMR and IR spectroscopy. The compounds will be subjected to intensive biological screening to determine their biological properties and application opportunities.","PeriodicalId":20537,"journal":{"name":"Proceedings of The 23rd International Electronic Conference on Synthetic Organic Chemistry","volume":"3 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of The 23rd International Electronic Conference on Synthetic Organic Chemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3390/ecsoc-23-06656","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Hydantoins and their sulfur containing analogues, thiohydantoins, are an important and interesting moiety. They represent a big group of structurally diverse compounds with intriguing physical, chemical and biological properties, which enabled them to be used in therapy, medicine in general, material science and industry. With the goal of broadening the set of potentially applicable hydantoin derivatives, we have synthesized a series of 2-thiohydantoins from vanillin and its derivatives, which themselves posses interesting biological properties. All compounds were fully characterized by NMR and IR spectroscopy. The compounds will be subjected to intensive biological screening to determine their biological properties and application opportunities.