M. Havenith, U. Heugen, A. Bergner, S. Ebbinghaus, E. Brundermann, E. Larios, D. Leitner, M. Gruebele
{"title":"THz-biology: studying protein dynamics in solution","authors":"M. Havenith, U. Heugen, A. Bergner, S. Ebbinghaus, E. Brundermann, E. Larios, D. Leitner, M. Gruebele","doi":"10.1109/ICIMW.2004.1422300","DOIUrl":null,"url":null,"abstract":"THz spectrometer to measure absorption spectra of solvated proteins is developed. The radiation source is a p-type germanium laser which delivers output powers of several watts in the THz regime (from 1-4 THz). Experimental results for different mutants of ubiquitin and /spl lambda/-repressor which serve as prototype systems is presented and compared with theoretical studies using molecular dynamics simulation.","PeriodicalId":13627,"journal":{"name":"Infrared and Millimeter Waves, Conference Digest of the 2004 Joint 29th International Conference on 2004 and 12th International Conference on Terahertz Electronics, 2004.","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2004-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Infrared and Millimeter Waves, Conference Digest of the 2004 Joint 29th International Conference on 2004 and 12th International Conference on Terahertz Electronics, 2004.","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ICIMW.2004.1422300","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
THz spectrometer to measure absorption spectra of solvated proteins is developed. The radiation source is a p-type germanium laser which delivers output powers of several watts in the THz regime (from 1-4 THz). Experimental results for different mutants of ubiquitin and /spl lambda/-repressor which serve as prototype systems is presented and compared with theoretical studies using molecular dynamics simulation.
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