Development, Standardization and Microbiological appraisal of Herbal Dentifrice prepared from Achyranthes aspera Linn. (Apamarga) leaves

Ganesh Asnotikar, Anusha Shetty, Dhananjaya Dhananjaya, Mithun C., R. Nayak, Shilpashree V. K.
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Abstract

Dentifrices are the products which are important in our daily life and mainly used to maintain good oral hygiene. The oral hygiene can be maintained throughout the day by using a variety of dentifrices prepared by herbal and synthetic ingredients. Most of the synthetic preparation of dentifrices causes side effects. In this study an attempt is made to prepare a tooth powder which can be used as a tool for proper oral hygiene and to overcome the side effects of synthetic one. The tooth powder was developed using various herbal ingredients such as Apamarga, Clove, Triphala, Pacha karpoora, Ritha and Mulethi. Developed formulation was standardized by analysing necessary evaluation parameters such as organoleptic, microscopical, physicochemical, rheological, phytochemical characteristics. The formulation was screened for its antimicrobial activity by agar well diffusion method against Streptococcus aureus. The results showed that the developed dentifrice has promising antimicrobial effect to use against dental diseases.
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牛膝草制剂的开发、标准化及微生物学评价。(Apamarga)离开
牙膏是我们日常生活中很重要的产品,主要用于保持良好的口腔卫生。通过使用各种草药和合成成分配制的牙膏,可以全天保持口腔卫生。大多数牙膏的合成制剂都有副作用。本研究试图制备一种既可作为良好口腔卫生的工具,又能克服人工牙粉的副作用的牙粉。这种牙粉是用各种草药成分制成的,比如阿帕玛加、丁香、Triphala、Pacha karpoora、Ritha和Mulethi。通过分析必要的评价参数,如感官、显微、理化、流变学、植物化学等,对所研制的制剂进行了标准化。采用琼脂孔扩散法对该制剂进行了抗菌活性筛选。结果表明,所研制的牙膏具有良好的抗菌效果。
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