Leiomyosarcoma of the oral cavity: Report of seven cases and review of literature

Abstract

Leiomyosarcoma is a relatively uncommon tumor that exhibits smooth muscle differentiation. Occurrence of this neoplasm in the oral cavity is exceedingly rare. Presenting signs and symptoms of leiomyosarcoma in the oral region are generally non-specific. The tumour is commonly encountered as a slow growing, discreet firm, and non-ulcerated painless mass. The physical appearance of these tumors can be deceptively benign and can also be mistaken for non-malignant conditions. Due to its innocuous clinical presentation and similarity to certain benign lesions it is critical for the dental surgeon to be familiar with this unusual lesion, as early diagnosis and aggressive initial treatment remains the mainstay of therapy for a good prognosis. This article presents seven cases of primary leiomyosarcoma in the oral region and highlights the need for early prudent diagnosis and treatment, without which may lead to a very poor out come of ill-fated patients.