Anti-Candida activity of terpenes from Salvia ovalifolia, S. procurrens and S. uliginosa, native to South Brazil

Cristiano Da Silva Sousa, L. Mezzomo, J. Butzge, G. Meirelles, S. Bordignon, G. V. von Poser, M. Apel
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Abstract

The essential oils of Salvia ovalifolia, S. procurrens and S. uliginosa were obtained by hydrodistillation and analyzed by gas chromatography-mass spectrometry. The three species displayed very low amounts of essential oils, consisting of a few sesquiterpenes, and aliphatic compounds such as aldehydes and long-chain fatty acids. From the leaves of S. uliginosa, an exudate was obtained which presented the diterpene icetexone as the major component. The exudate and icetexone were evaluated for the activity against Candida species, both showing inhibition of fungal growth.    
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巴西南部原产鼠尾草、小鼠尾草和小鼠尾草萜类抗念珠菌活性研究
采用加氢蒸馏法提取了鼠尾草、水仙和木犀草的精油,并采用气相色谱-质谱联用技术对其进行了分析。这三个物种的精油含量非常低,精油由几种倍半萜和脂肪族化合物组成,如醛和长链脂肪酸。从木臭叶中分离出一种以二萜烯酮为主要成分的分泌物。研究结果表明,液和冰替酮对念珠菌均有抑制作用。
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