Electrochemical behavior of Metronidazole (MNZ) at glassy carbon electrode at different concentrations

R. Das, Aayushi Chanderiya, A. Roy, S. Kashaw
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Abstract

A robust and straightforward electrochemical methodology based on electrochemical detection of Metronidazole (MNZ) at glassy carbon electrodes was suggested to determine. MNZ formed well-defined reversible cyclic voltammograms on the glassy carbon electrode in the Britton Robinson buffer solution. Various parameters' effects on voltammetric results were also evaluated. For MNZ determination, a differential pulse voltammetric model was introduced and developed. Excellent recovery results for spiked MNZ in pharmaceutical tablet samples were obtained, with recovery rates ranging from 97.44 to 97.51 percent.
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不同浓度甲硝唑在玻碳电极上的电化学行为
提出了一种在玻碳电极上检测甲硝唑(MNZ)的简便易行的电化学方法。MNZ在布里顿罗宾逊缓冲溶液中的玻碳电极上形成了明确的可逆循环伏安图。并评价了各参数对伏安结果的影响。为了测定MNZ,引入并发展了差分脉冲伏安法模型。加标后的MNZ在片剂样品中的回收率为97.44% ~ 97.51%,具有良好的回收率。
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