CHOROIDAL NEOVASCULARIZATION ASSOCIATED WITH BEST’S DISEASE

C. Gómez, L. D. Juan-Marcos, R. Lorenzo-Pérez, Álvaro Casado-Blanco, Vanesa Rivero-Gutiérrez, E. Hernández-Galilea
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Abstract

Best’s Disease is a macular dystrophy characterized by a lipofuscin accumulation on the retinal pigment epithelium. Five stages have been described based on fundus examination, including choroidal neovascularization. We report a case of a 59-years-old male, presented to the ophthalmologic department with visual loss in both eyes. Fundus examination revealed vitelliform lesions in both maculas. Fluorescein angiography showed a choroidal neovascularization in the left eye. The electrooculogram confirmed the diagnosis of Best's disease. Choroidal neovascularization is a rare complication of Best’s Disease in late stages. The most effective therapeutic options are photodynamic therapy with veteporfirin and antiangiogenic therapy.
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与贝氏病相关的脉络膜新生血管
贝斯特病是一种黄斑营养不良,其特征是视网膜色素上皮上的脂褐素积聚。根据眼底检查描述了五个阶段,包括脉络膜新生血管。我们报告一个59岁男性的病例,呈现给眼科的视力丧失在双眼。眼底检查显示两个黄斑有卵黄样病变。荧光素血管造影显示左眼脉络膜新生血管。眼电图证实了贝斯特氏病的诊断。脉络膜新生血管是贝斯特病晚期罕见的并发症。最有效的治疗选择是光动力治疗与veteporfirin和抗血管生成治疗。
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