Mini-Review of Analytical Methods used in Quantification of Ellagic Acid

IF 3.6 3区化学 Q2 CHEMISTRY, ANALYTICAL Reviews in Analytical Chemistry Pub Date : 2020-01-01 DOI:10.1515/revac-2020-0113

O. Agrawal, Yogesh A. Kulkarni

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引用次数: 7

Abstract

Abstract Ellagic acid is an important phytochemical present in different plants such as Strawberry, Grapes, Blackberry, Raspberry etc. Chemically, ellagic acid is 2, 3, 7, 8-tetrahydroxychromeno [5, 4, 3-cde] chromene-5, 10-dione. It is an organic heterotetracyclic compound resulting from the dimerization of gallic acid molecules by oxidative aromatic coupling with intramolecular lactonization. Ellagic acid has been reported for various pharmacological activities such as anti-inflammatory, neuroprotective, cardioprotective, antioxidant, anti-mutagenic etc. Various analytical methods based on spectrophotometry, chromatography, hyphenated techniques, capillary zone electrophoresis etc. have been developed for identification and quantification of ellagic acid in natural sources and formulations. The present review provides detailed information on quantitative analysis of ellagic acid present in Strawberry, Grapes, Blackberry, Raspberry, Cranberry; Syzygium cumini seed extract, Woodfordia fruticosa plant extract, Potentilla species extracts etc. It also focuses on analytical methods for quantification of ellagic acid in herbal and traditional formulations such as Ashwagandharishta, Triphala churna, Dhatrinisha churna, Arjunarishta, Manjisthadi churna.

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鞣花酸定量分析方法综述

鞣花酸是一种重要的植物化学物质，存在于草莓、葡萄、黑莓、覆盆子等植物中。从化学上讲，鞣花酸是2,3,7,8 -四羟基- [5,4,3 -cde] - 5,10 -二酮。它是一种有机杂四环化合物，由没食子酸分子通过氧化芳偶联和分子内内酯化而成。鞣花酸具有抗炎、神经保护、心脏保护、抗氧化、抗诱变等药理作用。基于分光光度法、色谱法、联用技术、毛细管区带电泳等多种分析方法已被开发用于鉴定和定量天然来源和配方中的鞣花酸。综述了草莓、葡萄、黑莓、覆盆子、蔓越莓中鞣花酸的定量分析方法;小茴香种子提取物、木贼草提取物、蕨草提取物等。它还侧重于草药和传统配方中鞣花酸的定量分析方法，如Ashwagandharishta, Triphala churna, Dhatrinisha churna, Arjunarishta, Manjisthadi churna。

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来源期刊

Reviews in Analytical Chemistry 化学-分析化学

CiteScore

7.50

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Reviews in Analytical Chemistry publishes authoritative reviews by leading experts in the dynamic field of chemical analysis. The subjects can encompass all branches of modern analytical chemistry such as spectroscopy, chromatography, mass spectrometry, electrochemistry and trace analysis and their applications to areas such as environmental control, pharmaceutical industry, automation and other relevant areas. Review articles bring the expert up to date in a concise manner and provide researchers an overview of new techniques and methods.