Ten years experience in surgical management of congenital lung malformations: A prospective, cross sectional study

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL Journal of Clinical Sciences Pub Date : 2022-04-01 DOI:10.4103/jcls.jcls_53_21
E. Ogunleye, O. Olusoji, I. Fajolu, Peter J Iwuchukwu
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Abstract

Background: Congenital lung malformations are very rare lung lesions caused by abnormal lung development occurring at different stages of intrauterine life. They are a spectrum of congenital malformations involving the trachea-bronchial tree, pulmonary parenchyma, and the blood vessels. They are a family of pulmonary lesions that include congenital pulmonary airway malformations (CPAM), bronchopulmonary sequestrations, bronchogenic cysts (BC), and congenital lobar emphysema (CLE). The aim of the study is to determine the pattern of congenital malformation of the lungs and the outcomes of treatment in Lagos. Methods: This is a prospective study of all patients with congenital lung malformations referred to our center in the period between January 2011 and December 2020. All pediatric cases were diagnosed by the pediatricians in our center and confirmed with chest computed tomography (CT) scan. The adult cases were equally confirmed with a chest CT scan. The lesions encountered in this study include BC, CPAM, bronchopulmonary sequestrations, lung hypoplasia (LH), CLE, and pulmonary arterio-venous malformations. Data collected include biodata, type of malformation, mode of management (surgery), and postoperative outcome and were analyzed as percentages and mean. Results: A total of 18 patients who were diagnosed with congenital lung malformations were recruited into this study. The congenital malformations included CLE, CPAM, BC, lung sequestration, LH, and arterio-venous malformation of the lung. Children accounted for 78% (13) of the population, while the adult population was 28%.(5) The neonates constituted 22% (4) with a mean age of 7.5 ± 5.1, whilst the older children made up 50%, with a mean age of 18.8 ± 10.7 months. The mean age of the adult population was 39 ± 15 years. Seventeen (94.41) had surgery, whilst one opted for continued medical surveillance. Two patients died from postoperative respiratory failure. Conclusion: Congenital lung malformations, though rare, are a heterogeneous group of diseases with presentation, ranging from neonatal respiratory distress to asymptomatic presentation in the adult. The mainstay of management remains surgery with a reasonably good outcome.
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先天性肺畸形手术治疗的十年经验:一项前瞻性横断面研究
背景:先天性肺畸形是一种非常罕见的肺部病变,发生在子宫内不同阶段的肺发育异常。它们是一种涉及气管-支气管树、肺实质和血管的先天性畸形。它们是一个肺病变家族,包括先天性肺气道畸形(CPAM)、支气管肺隔离、支气管源性囊肿(BC)和先天性肺气肿(CLE)。该研究的目的是确定肺部先天性畸形的模式和拉各斯治疗的结果。方法:对2011年1月至2020年12月至本中心就诊的所有先天性肺畸形患者进行前瞻性研究。所有患儿均由本中心儿科医师诊断,并行胸部CT扫描确诊。成人病例同样通过胸部CT扫描得到证实。本研究中遇到的病变包括BC、CPAM、支气管肺隔离、肺发育不全(LH)、CLE和肺动静脉畸形。收集的数据包括生物资料、畸形类型、处理方式(手术)和术后结果,并以百分比和平均值进行分析。结果:本研究共招募了18例诊断为先天性肺畸形的患者。先天性畸形包括CLE、CPAM、BC、肺隔离、LH和肺动静脉畸形。(5)新生儿占22%(4),平均年龄为7.5±5.1个月,年龄较大的儿童占50%,平均年龄为18.8±10.7个月。成人平均年龄39±15岁。17人(94.41人)接受了手术,1人选择继续接受医疗监测。2例患者死于术后呼吸衰竭。结论:先天性肺畸形,虽然罕见,是一个异质组疾病的表现,从新生儿呼吸窘迫到成人无症状表现。治疗的主要方法仍然是手术,其预后相当好。
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来源期刊
Journal of Clinical Sciences
Journal of Clinical Sciences MEDICINE, GENERAL & INTERNAL-
自引率
0.00%
发文量
15
审稿时长
45 weeks
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