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Neck circumference and cardiometabolic syndrome in adult patients at a tertiary hospital in Lagos, Nigeria: A cross-sectional study 尼日利亚拉各斯一家三级医院成年患者的颈围与心脏代谢综合征:横断面研究
IF 0.1 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-07-01 DOI: 10.4103/jcls.jcls_10_23
A. Dada, Amisu Mumani, B. Okunowo
Background: Cardiometabolic syndrome (CMS) is an emerging problem of public health importance in low- and middle-income countries like Nigeria, resulting in a significant increase in morbidity and mortality. Studies from other regions have suggested using neck circumference (NC) values for predicting CMS. This study explores the utility of this approach among patients seen at a tertiary facility in Lagos, Nigeria. Methods: This was a hospital-based, descriptive cross-sectional study. Participants were adult patients managed and seen in the follow-up clinics of the endocrinology unit. NC of >37 cm or >34 cm in males and females was considered abnormal. Data were analyzed using the Statistical Package for the Social Sciences (SPSS) version 28.0. Results: A total of 202 patients were recruited (mean age [standard deviation]: 61.5 [12.2] years). The prevalence of CMS was 79.2%, with hypertension being the most prevalent cardiometabolic risk (85.1%). The mean NCs were 38.9 (4.2) cm for men and 36.0 (2.9) cm for women, with 67.8% of participants having abnormal values. NC was significantly correlated with diastolic blood pressure (DBP) (P = 0.028), but not other components of CMS among participants. On receiver operating curve (ROC) analysis, NC was not significantly predictive of CMS (females: area under the curve [AUC]: 0.616 [P = 0.068]; males: AUC: 0.0469 [P = 0.080]). Conclusion: This study revealed a high prevalence of metabolic syndrome among participants. There was a significant correlation between NC and other anthropometric indices, but not with the components of CMS, except DBP. On ROC analysis, NC was not significantly related to CMS. The study's findings suggest that NC is not a useful predictor of CMS in this population.
背景:在尼日利亚等中低收入国家,心脏代谢综合征(CMS)是一个新出现的具有重要公共卫生意义的问题,导致发病率和死亡率大幅上升。其他地区的研究建议使用颈围(NC)值来预测 CMS。本研究探讨了这种方法在尼日利亚拉各斯一家三级医疗机构就诊患者中的实用性。方法:这是一项基于医院的描述性横断面研究。参与者为在内分泌科随访门诊接受管理和就诊的成年患者。男性和女性的 NC >37 厘米或 >34 厘米被视为异常。数据采用社会科学统计软件包(SPSS)28.0 版进行分析。结果共招募了 202 名患者(平均年龄 [标准差]:61.5 [12.2] 岁)。CMS 患病率为 79.2%,高血压是最常见的心脏代谢风险(85.1%)。男性的平均 NC 值为 38.9 (4.2) 厘米,女性为 36.0 (2.9) 厘米,67.8% 的参与者数值异常。NC与舒张压(DBP)有明显相关性(P = 0.028),但与 CMS 的其他组成部分无关。根据接收器操作曲线(ROC)分析,NC 对 CMS 的预测作用不明显(女性:曲线下面积 [AUC]:0.616 [P = 0.068];男性:AUC:0.0469 [P = 0.080]).结论这项研究显示,参与者中代谢综合征的发病率很高。NC与其他人体测量指数之间存在明显的相关性,但与代谢综合征的组成部分(DBP除外)之间不存在明显的相关性。在 ROC 分析中,NC 与 CMS 的关系并不明显。研究结果表明,在这一人群中,NC 并非预测 CMS 的有效指标。
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引用次数: 0
Intensive care management of sniper (organophosphate) poisoning secondary to deliberate self-harm: A case report 对蓄意自残导致的狙击手(有机磷)中毒进行重症监护:病例报告
IF 0.1 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-07-01 DOI: 10.4103/jcls.jcls_1_23
Olumuyiwa Ajayeoba, Simeon Olateju, Olurotimi Aaron, A. Faponle, M. Komolafe, A. Adebowale, Akinsulore Adesanmi
Sniper, an insecticide made of synthetic organophosphate, is a choice substance used for suicide in Nigeria among the youth due to its ready availability. The aim of this study was to describe the management of a case of organophosphate poisoning. A 24-year-old male medical student presented on account of loss of consciousness for 2 h, with vomiting, the passage of loose stool, and a preceding history of suicidal ideation. He was found in his room with an empty bottle of sniper. The patient was in obvious respiratory distress with excessive salivation. His baseline vital sign was as follows: pulse rate-124 bpm, blood pressure-150/80 mmHg, respiratory rate of 34 cpm, SpO2 86%, and temperature of 36.8°C. He was intubated, admitted into the intensive care unit, and placed on a mechanical ventilator. He was commenced on intravenous (IV) atropine 2 mg stat and IV glycopyrrolate 0.4 mg 8 hourly. On the 4th day, he was placed on IV atropine infusion 1 mg/h, while IV phenytoin 300 mg stat and then 150 mg nocte were commenced on account of provoked seizure. The patient had the IV atropine infusion for 10 days. He was placed on midazolam infusion for sedation and had potassium and magnesium correction. The patient was subsequently extubated, transferred to the ward, and discharged home after 10 days in the ward. Organophosphate poisoning management could be challenging and fatal. Early presentation, prompt and appropriate airway management, use of atropine infusion, prompt use of antibiotics, and other supportive care can improve survival.
在尼日利亚,"狙击手 "是一种由人工合成的有机磷制成的杀虫剂,由于唾手可得,成为年轻人自杀的首选药物。本研究旨在描述一例有机磷中毒病例的处理方法。一名 24 岁的男性医科学生因意识丧失 2 小时,伴有呕吐、大便稀溏,并有自杀倾向而就诊。在他的房间里发现了一瓶空的狙击药。患者明显呼吸困难,唾液分泌过多。他的生命体征基线如下:脉搏-124 bpm,血压-150/80 mmHg,呼吸频率 34 cpm,SpO2 86%,体温 36.8°C。他被插管,送入重症监护室,并上了机械呼吸机。他开始静脉注射阿托品 2 毫克(静注)和甘草酸苷 0.4 毫克(静注),每小时 8 次。第 4 天,他开始静脉注射阿托品 1 毫克/小时,同时开始静脉注射苯妥英 300 毫克(静注),随后因诱发癫痫发作又开始静脉注射 150 毫克(夜用)。阿托品静脉注射持续了 10 天。他接受了咪达唑仑输液镇静,并进行了钾镁校正。随后,患者被拔除气管,转入病房,在病房住了 10 天后出院回家。有机磷中毒的处理可能具有挑战性和致命性。及早就诊、及时进行适当的气道管理、使用阿托品输液、及时使用抗生素和其他支持性护理可提高存活率。
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引用次数: 0
Effect of overground gait training with rhythmic auditory stimulation on lower limb motor coordination and activities of daily living in stroke survivors: A cross-sectional study 通过有节奏的听觉刺激进行地面步态训练对脑卒中幸存者下肢运动协调性和日常生活活动的影响:横断面研究
IF 0.1 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-07-01 DOI: 10.4103/jcls.jcls_31_23
Oladunni Osundiya, Olamide Joseph, O. Olawale
Background: Overground walking exercise training is often employed as part of the community-based stroke rehabilitation program. The aim of this study was to investigate the effect of overground gait training (OGT) with rhythmic auditory stimulation (RAS) on lower limb motor coordination and activities of daily living in stroke survivors. Methods: Twenty-eight stroke survivors were randomly assigned into two groups. Participants in Group A had OGT, while those in Group B had OGT with RAS twice a week for 6 weeks. Lower-extremity motor coordination test was used to assess lower limb motor coordination, while activities of daily living were assessed with Nottingham Extended Activities of Daily Living (NEADL). Repeated measures analysis was used for within-group comparisons of the LEMOCOT scores, while Friedman's test was used for within-group comparisons of NEADL scores. Linear mixed effect regression model was used to compare the LEMOCOT scores between the groups, while Mann–Whitney U-test was used to compare the NEADL scores between the groups (P ≤ 0.05). Results: The mean values of LEMOCOT scores for the paretic limb and nonparetic limb (9.14; 8.43) improved significantly at the 3rd and 6th weeks (9.86, 10.21; 19.36, 20.29), respectively, among participants in Group A. There was a significant improvement in the mean rank of the NEADL in the 6th week (2.39) compared with the baseline (1.64). In Group B, the mean values of LEMOCOT scores for the paretic limb and nonparetic limb (9.43, 18.79) improved by the 3rd and 6th weeks (11.29, 20.14; 11.71, 20.29). The mean rank of the NEADL at baseline (1.61) improved significantly in the 6th week (2.39). Conclusion: OGT with or without RAS is effective in improving lower limb motor coordination and activities of daily living among stroke survivors.
背景:地面步行运动训练通常是社区脑卒中康复计划的一部分。本研究的目的是调查带有节奏性听觉刺激(RAS)的地面步态训练(OGT)对脑卒中幸存者下肢运动协调性和日常生活活动的影响。研究方法将 28 名中风幸存者随机分为两组。A 组接受 OGT,B 组接受 OGT 和 RAS,每周两次,持续 6 周。下肢运动协调测试用于评估下肢运动协调性,而日常生活活动则通过诺丁汉日常生活扩展活动(NEADL)进行评估。LEMOCOT 评分的组内比较采用重复测量分析法,NEADL 评分的组内比较采用弗里德曼检验法。线性混合效应回归模型用于比较组间的 LEMOCOT 分数,曼-惠特尼 U 检验用于比较组间的 NEADL 分数(P ≤ 0.05)。结果A组患者瘫痪肢体和非瘫痪肢体的LEMOCOT评分均值(9.14;8.43)在第3周和第6周分别显著提高(9.86,10.21;19.36,20.29)。在 B 组中,瘫痪肢体和非瘫痪肢体的 LEMOCOT 平均值(9.43,18.79)在第 3 周和第 6 周有所改善(11.29,20.14;11.71,20.29)。基线时的 NEADL 平均等级(1.61)在第 6 周显著提高(2.39)。结论无论是否采用 RAS,OGT 都能有效改善中风幸存者的下肢运动协调性和日常生活活动能力。
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引用次数: 0
Erratum: Fall risks and health-related quality of life among elderly attending primary healthcare centers in South Western Nigeria: A cross-sectional study 勘误:尼日利亚西南部初级保健中心就诊老年人的跌倒风险和与健康相关的生活质量:横断面研究
IF 0.1 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-07-01 DOI: 10.4103/2468-6859.389443
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引用次数: 0
The Journal of Clinical Sciences: From humble beginnings to a dissemination force of scientific research 临床科学杂志》:从默默无闻到科学研究的传播力量
IF 0.1 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-07-01 DOI: 10.4103/jcls.jcls_99_23
Adesoji O. Ademuyiwa
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引用次数: 0
Comparison of Alvarado score, Raja Isteri Pengiran Anak Saleha Appendicitis score, and ultrasonography for diagnosing acute appendicitis: A prospective study 阿尔瓦拉多评分、Raja Isteri Pengiran Anak Saleha 阑尾炎评分和超声波检查诊断急性阑尾炎的比较:前瞻性研究
IF 0.1 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-07-01 DOI: 10.4103/jcls.jcls_25_23
Mohan Lal, Anil Kumar, P. Chandawat
Background: Different methods for diagnosing acute appendicitis have been invented to help amid equivocal instances. Different levels of accuracy have been noted when the imaging and scores were utilized in diverse populations and health-care contexts. Ultrasonography (USG) is a widely accessible and safe imaging technique, but it is operator dependent. Since USG, Alvarado scores, and Raja Isteri Pengiran Anak Saleha Appendicitis (RIPASA) score have never been thoroughly compared, we practiced them to people who suffered from right iliac fossa pain and were thought to have acute appendicitis. Methods: Evaluation scoring sheets, including all the elements of both scores, as well as USG findings, demographic data, and histological reports, were employed. Specificity, sensitivity, negative predictive value, positive predictive value, predicted negative appendectomy rate, and diagnostic accuracy for both scores as well as USG were determined and compared. Results: As compared to the Alvarado score and USG (75.46% and 71.78%, respectively), the RIPASA score's diagnostic accuracy of 89.57% was significantly higher. According to the USG, Alvarado, and RIPASA scores, the predicted negative appendectomy rates were 17.82%, 9.195%, and 6.48%, respectively. Conclusion: The RIPASA score is an affordable, trustworthy, repeatable diagnostic tool with high accuracy for the detection of acute appendicitis.
背景:人们发明了不同的方法来诊断急性阑尾炎,以便在诊断不明确的情况下提供帮助。在不同的人群和医疗环境中使用不同的成像和评分方法时,准确度也不尽相同。超声波成像(USG)是一种广泛使用且安全的成像技术,但它依赖于操作者。由于 USG、Alvarado 评分和 Raja Isteri Pengiran Anak Saleha Appendicitis(RIPASA)评分从未进行过全面比较,因此我们对患有右髂窝疼痛并被认为患有急性阑尾炎的人进行了练习。方法采用评估评分表,包括两个评分表的所有要素,以及 USG 结果、人口统计学数据和组织学报告。确定并比较两种评分和 USG 的特异性、敏感性、阴性预测值、阳性预测值、预测的阑尾切除阴性率和诊断准确性。结果:与阿尔瓦拉多评分和 USG(分别为 75.46% 和 71.78%)相比,RIPASA 评分的诊断准确率高达 89.57%,明显更高。根据 USG、Alvarado 和 RIPASA 评分,预测的阑尾切除阴性率分别为 17.82%、9.195% 和 6.48%。结论RIPASA 评分是一种经济实惠、值得信赖、可重复使用的诊断工具,在检测急性阑尾炎方面具有很高的准确性。
{"title":"Comparison of Alvarado score, Raja Isteri Pengiran Anak Saleha Appendicitis score, and ultrasonography for diagnosing acute appendicitis: A prospective study","authors":"Mohan Lal, Anil Kumar, P. Chandawat","doi":"10.4103/jcls.jcls_25_23","DOIUrl":"https://doi.org/10.4103/jcls.jcls_25_23","url":null,"abstract":"Background: Different methods for diagnosing acute appendicitis have been invented to help amid equivocal instances. Different levels of accuracy have been noted when the imaging and scores were utilized in diverse populations and health-care contexts. Ultrasonography (USG) is a widely accessible and safe imaging technique, but it is operator dependent. Since USG, Alvarado scores, and Raja Isteri Pengiran Anak Saleha Appendicitis (RIPASA) score have never been thoroughly compared, we practiced them to people who suffered from right iliac fossa pain and were thought to have acute appendicitis. Methods: Evaluation scoring sheets, including all the elements of both scores, as well as USG findings, demographic data, and histological reports, were employed. Specificity, sensitivity, negative predictive value, positive predictive value, predicted negative appendectomy rate, and diagnostic accuracy for both scores as well as USG were determined and compared. Results: As compared to the Alvarado score and USG (75.46% and 71.78%, respectively), the RIPASA score's diagnostic accuracy of 89.57% was significantly higher. According to the USG, Alvarado, and RIPASA scores, the predicted negative appendectomy rates were 17.82%, 9.195%, and 6.48%, respectively. Conclusion: The RIPASA score is an affordable, trustworthy, repeatable diagnostic tool with high accuracy for the detection of acute appendicitis.","PeriodicalId":15490,"journal":{"name":"Journal of Clinical Sciences","volume":"49 1","pages":"80 - 86"},"PeriodicalIF":0.1,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139365826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Knowledge and preventive practices regarding malnutrition among mothers of under-fives in Kaduna North Local Government Area: A descriptive cross-sectional study 卡杜纳北部地方政府区五岁以下儿童母亲营养不良的知识和预防措施:一项描述性横断面研究
IF 0.1 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-04-01 DOI: 10.4103/jcls.jcls_2_23
B. Nwankwo, Mary Kakamor, N. Usman, V. Omole, A. Oyefabi
Background: Malnutrition (undernutrition) and its attendant complications remain the plight of many countries globally. However, sub-Saharan Africa is disproportionately affected with the burden of this largely preventable condition. Basic knowledge of nutrition and good feeding practices among caregivers are essential to reduce childhood malnutrition. The aim of this study was to determine the knowledge and preventive practices related to malnutrition among mothers of children aged <5 years in Kaduna North Local Government Area. Methods: This was a cross-sectional descriptive study that was carried out to determine the knowledge and preventive practices related to malnutrition among mothers of children aged <5 years. A multistage sampling technique was used to select 262 mothers of children aged <5 years, from whom data were collected using interviewer-administered questionnaires. Data were analyzed using SPSS version 25. Results: The mean age of the respondents was 27.5 ± 3.5 years. The majority of the respondents, 164 (62.6%), had secondary school education. Only 11.5% of the respondents had good knowledge on malnutrition. Almost one-third (30.9%) of the respondents had good preventive practices regarding malnutrition. There was a statistically significant relationship between respondents' knowledge of malnutrition and their educational status (P < 0.0001), occupation (P < 0.0001), and the number of children they have (P < 0.0001). There was a statistically significant relationship between respondents' preventive practice regarding malnutrition and their educational status (P < 0.0001) and occupation (P < 0.0001). Conclusion: In view of the findings of poor knowledge and practice among the respondents, improving female education will lead to better nutritional outcomes among their children.
背景:营养不良(营养不足)及其并发症仍然是全球许多国家的困境。然而,撒哈拉以南非洲受到这一基本上可预防疾病负担的不成比例的影响。照料者掌握营养的基本知识和良好喂养做法对于减少儿童营养不良至关重要。本研究的目的是确定卡杜纳北部地方政府区5岁以下儿童的母亲与营养不良有关的知识和预防措施。方法:这是一项横断面描述性研究,旨在确定5岁以下儿童母亲的营养不良相关知识和预防措施。采用多阶段抽样方法,选取262名5岁以下儿童的母亲,采用访谈式问卷收集数据。数据分析采用SPSS version 25。结果:患者平均年龄27.5±3.5岁。大多数受访者(164人,占62.6%)受过中学教育。只有11.5%的受访者对营养不良有良好的了解。几乎三分之一(30.9%)的答复者在营养不良方面采取了良好的预防措施。被调查者对营养不良的认知与受教育程度(P < 0.0001)、职业(P < 0.0001)、子女数量(P < 0.0001)存在显著的相关关系。被调查者对营养不良的预防行为与其受教育程度(P < 0.0001)和职业(P < 0.0001)有统计学意义。结论:鉴于调查对象的知识和实践不足,提高女性教育水平将有助于改善其子女的营养状况。
{"title":"Knowledge and preventive practices regarding malnutrition among mothers of under-fives in Kaduna North Local Government Area: A descriptive cross-sectional study","authors":"B. Nwankwo, Mary Kakamor, N. Usman, V. Omole, A. Oyefabi","doi":"10.4103/jcls.jcls_2_23","DOIUrl":"https://doi.org/10.4103/jcls.jcls_2_23","url":null,"abstract":"Background: Malnutrition (undernutrition) and its attendant complications remain the plight of many countries globally. However, sub-Saharan Africa is disproportionately affected with the burden of this largely preventable condition. Basic knowledge of nutrition and good feeding practices among caregivers are essential to reduce childhood malnutrition. The aim of this study was to determine the knowledge and preventive practices related to malnutrition among mothers of children aged <5 years in Kaduna North Local Government Area. Methods: This was a cross-sectional descriptive study that was carried out to determine the knowledge and preventive practices related to malnutrition among mothers of children aged <5 years. A multistage sampling technique was used to select 262 mothers of children aged <5 years, from whom data were collected using interviewer-administered questionnaires. Data were analyzed using SPSS version 25. Results: The mean age of the respondents was 27.5 ± 3.5 years. The majority of the respondents, 164 (62.6%), had secondary school education. Only 11.5% of the respondents had good knowledge on malnutrition. Almost one-third (30.9%) of the respondents had good preventive practices regarding malnutrition. There was a statistically significant relationship between respondents' knowledge of malnutrition and their educational status (P < 0.0001), occupation (P < 0.0001), and the number of children they have (P < 0.0001). There was a statistically significant relationship between respondents' preventive practice regarding malnutrition and their educational status (P < 0.0001) and occupation (P < 0.0001). Conclusion: In view of the findings of poor knowledge and practice among the respondents, improving female education will lead to better nutritional outcomes among their children.","PeriodicalId":15490,"journal":{"name":"Journal of Clinical Sciences","volume":"1 1","pages":"52 - 58"},"PeriodicalIF":0.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78738194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The prevalence of impaired fasting glucose, undiagnosed diabetes mellitus, and associated risk factors among adults presented in the outpatient department in Mogadishu Somalia: A cross-sectional study 索马里摩加迪沙门诊成人中空腹血糖受损、未确诊糖尿病及相关危险因素的患病率:一项横断面研究
IF 0.1 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-04-01 DOI: 10.4103/jcls.jcls_27_23
A. Bashir, O. Fiidow, A. Mohamud
Background: Diabetes is a major health concern that has grown to alarming proportions. With more than 500 million sufferers globally, diabetes is one of the most prevalent metabolic diseases. The aim of the study is to find the prevalence of impaired fasting glucose (IFG) and undiagnosed diabetes mellitus (DM) in patients presented to our outpatient department at Mogadishu Somali Turkey Training and Research Hospital. Methods: In this cross-sectional study conducted in the largest referral hospital in Mogadishu Somalia, all adult patients who volunteered to give consent have participated in the study. We excluded pregnant women, individuals taking medications that could affect glucose metabolism (e.g., steroids, beta-blockers, and thiazide diuretics), and confirmed diabetic patients from our study. Results: Seven hundred and twenty-two adults with a mean age of 42.85 ± 18.23 years were included. Most of the participants were female 432 (59.8%), aged 20–40 years 329 (45.6%). The prevalence of IFG was common among males (22.4%) and those 60 years and above (30.6%), while the prevalence of undiagnosed DM was high among males (9.7%), aged 40–60 years (13.4%). In the bivariate analysis, total cholesterol, high-density lipoprotein, triglycerides, systolic blood pressure, and comorbidities were found to be significantly associated with the prevalence of IFG in all age groups. Conclusions: IFG was common among outpatient adults. Increased urbanization, the rise of the middle class, and population aging will lead to considerable rises in IFG, undiagnosed diabetes, and diabetes in Somalia in the next years. To limit the growth of diabetes in Somalia, public health interventions must be implemented soon. Promoting the health system and providing education can help.
背景:糖尿病是一个主要的健康问题,已经发展到令人担忧的程度。全球糖尿病患者超过5亿,是最普遍的代谢性疾病之一。本研究的目的是发现在摩加迪沙索马里土耳其培训和研究医院门诊部就诊的患者中空腹血糖受损(IFG)和未确诊糖尿病(DM)的患病率。方法:在索马里摩加迪沙最大的转诊医院进行的横断面研究中,所有自愿同意的成年患者都参加了研究。我们排除了孕妇、服用可能影响葡萄糖代谢的药物(如类固醇、受体阻滞剂和噻嗪类利尿剂)的个体,以及研究中确诊的糖尿病患者。结果:纳入成人722人,平均年龄42.85±18.23岁。其中女性432人(59.8%),20 ~ 40岁329人(45.6%)。IFG患病率在男性(22.4%)和60岁及以上人群(30.6%)中较为普遍,而未确诊糖尿病患病率在40-60岁男性(9.7%)和40-60岁男性(13.4%)中较高。在双变量分析中,发现总胆固醇、高密度脂蛋白、甘油三酯、收缩压和合并症与所有年龄组的IFG患病率显著相关。结论:IFG在门诊成人中很常见。未来几年,城市化程度的提高、中产阶级的崛起和人口老龄化将导致索马里IFG、未确诊糖尿病和糖尿病的大幅上升。为了限制糖尿病在索马里的增长,必须尽快实施公共卫生干预措施。促进卫生系统和提供教育可以有所帮助。
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引用次数: 0
Surgical site infection in Nigerian patients: A comparative study of two prophylactic antibiotics 尼日利亚患者手术部位感染:两种预防性抗生素的比较研究
IF 0.1 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-04-01 DOI: 10.4103/jcls.jcls_24_23
G. Enweluzo, O. Akinmokun, E. Alabi, A. Ohadugha, S. Giwa
Background: Infection remains an important complication of surgical procedures. It is an important aspect of patient care as it can be a source of distress for the patients, and the healthcare system in terms of finance and psychological impact. The administration of appropriate prophylactic antibiotics is important in the prevention of surgical site infection (SSI). However, resistance to antibiotics by the micro-organisms is a growing concern in the healthcare industry. This study compared the infection rate between Ceftriaxone and Ceftriaxone-Tazobactam combination as surgical prophylaxis in Nigerian population. Method: This was a double blinded randomized study conducted at the Lagos University Teaching Hospital from October 2020 to September2021. Two hundred and forty (240) patients ,who were to have surgical procedures performed on them, were recruited and randomly distributed into two groups (A&B) of 120 patients each. Group A were those who had Ceftriaxone alone ,while group B were those who had combination of Ceftriaxone and Tazobactam. Results: There was no statistical difference in the demographic characteristics of the two groups .The crude infection rate was 3 .8 %. The infection rate in group A was 3 .3 % within the first week but increased to 4 .2 % in the second week. The infection rate in group B was 3 .3 % within the first week and second week. At 30 days, the infection rate within group A was 2 .5 % and 0 % in group B. Regression analysis showed advanced age (P =0 .003), level of education (P =0 .0001),prolonged duration of surgery (P =0 .012) and excessive blood loss (P =0 .0001) as the important factors associated with development of SSI in the patients included in the study. Conclusion: Surgical site infection remains an important complication following surgeries. Certain factors such as advanced age, prolonged surgery and excessive blood loss increase the risk for SSI. Efforts should be geared towards prevention of SSI in patients by modifying risk factors that are modifiable and using antibiotics with better infection rate as prophylaxis.
背景:感染仍然是外科手术的一个重要并发症。这是患者护理的一个重要方面,因为它可能是患者和医疗保健系统在财务和心理影响方面的痛苦来源。给予适当的预防性抗生素是预防手术部位感染(SSI)的重要。然而,微生物对抗生素的耐药性是医疗保健行业日益关注的问题。本研究比较了头孢曲松和头孢曲松-他唑巴坦联合手术预防在尼日利亚人群中的感染率。方法:这是一项双盲随机研究,于2020年10月至2021年9月在拉各斯大学教学医院进行。240名即将接受外科手术的患者被招募并随机分为两组(a组和b组),每组120名患者。A组为头孢曲松单用组,B组为头孢曲松与他唑巴坦合用组。结果:两组患者人口学特征差异无统计学意义,粗感染率为3.8%。A组第1周感染率为3.3%,第2周感染率上升至4.2%。B组第1周和第2周感染率为3.3%。30 d时,A组感染率为2.5%,b组感染率为0%。回归分析显示,高龄(P = 0.003)、文化程度(P = 0.0001)、手术时间延长(P = 0.012)和失血过多(P = 0.0001)是本组患者发生SSI的重要因素。结论:手术部位感染仍是术后重要并发症。高龄、手术时间延长和失血过多等因素会增加SSI的风险。应通过改变可改变的危险因素和使用感染率较高的抗生素作为预防措施,努力预防患者SSI。
{"title":"Surgical site infection in Nigerian patients: A comparative study of two prophylactic antibiotics","authors":"G. Enweluzo, O. Akinmokun, E. Alabi, A. Ohadugha, S. Giwa","doi":"10.4103/jcls.jcls_24_23","DOIUrl":"https://doi.org/10.4103/jcls.jcls_24_23","url":null,"abstract":"Background: Infection remains an important complication of surgical procedures. It is an important aspect of patient care as it can be a source of distress for the patients, and the healthcare system in terms of finance and psychological impact. The administration of appropriate prophylactic antibiotics is important in the prevention of surgical site infection (SSI). However, resistance to antibiotics by the micro-organisms is a growing concern in the healthcare industry. This study compared the infection rate between Ceftriaxone and Ceftriaxone-Tazobactam combination as surgical prophylaxis in Nigerian population. Method: This was a double blinded randomized study conducted at the Lagos University Teaching Hospital from October 2020 to September2021. Two hundred and forty (240) patients ,who were to have surgical procedures performed on them, were recruited and randomly distributed into two groups (A&B) of 120 patients each. Group A were those who had Ceftriaxone alone ,while group B were those who had combination of Ceftriaxone and Tazobactam. Results: There was no statistical difference in the demographic characteristics of the two groups .The crude infection rate was 3 .8 %. The infection rate in group A was 3 .3 % within the first week but increased to 4 .2 % in the second week. The infection rate in group B was 3 .3 % within the first week and second week. At 30 days, the infection rate within group A was 2 .5 % and 0 % in group B. Regression analysis showed advanced age (P =0 .003), level of education (P =0 .0001),prolonged duration of surgery (P =0 .012) and excessive blood loss (P =0 .0001) as the important factors associated with development of SSI in the patients included in the study. Conclusion: Surgical site infection remains an important complication following surgeries. Certain factors such as advanced age, prolonged surgery and excessive blood loss increase the risk for SSI. Efforts should be geared towards prevention of SSI in patients by modifying risk factors that are modifiable and using antibiotics with better infection rate as prophylaxis.","PeriodicalId":15490,"journal":{"name":"Journal of Clinical Sciences","volume":"1 1","pages":"59 - 64"},"PeriodicalIF":0.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82195830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thoracotomy in children: A decade review of indications and outcomes 儿童开胸术:十年适应症和结果回顾
IF 0.1 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2023-04-01 DOI: 10.4103/jcls.jcls_67_22
E. Ogunleye, O. Olusoji, O. Adekola
Background: Thoracotomy in children is relatively rare compared to adults. It can be very challenging due to the peculiar anatomy and physiology in this age group. The objective of the study was to study the indications, outcomes, and complications following thoracotomy. Methods: This was a retrospective analysis of the medical charts of neonates, infants, and children who had undergone thoracotomy under general anesthesia from January 2011 to December 2020 at our institution. Furthermore, we searched for the childhood thoracic diseases necessitating thoracotomy; the indications and complications following thoracotomy, as well as, the quality of life following thoracotomy. The children had either posterolateral or lateral thoracotomy, which spared the latissimus dorsi and/or serratus anterior. Data collected included demographics, surgical intervention, duration of intensive care unit admission, postoperative complications, and clinical outcome. Results: Out of the 39 patients, a majority were female 20 (51.3%), the most common indication for thoracotomy was congenital anomalies in 25 (64.1%) patients (lung malformations, 35.9% and patent ductus arteriosus, 28.2%), followed by foreign body aspiration (20.21%). Postoperative complications were seen in 15 (38.5%), out of whom 3 (20%) had atelectasis, chylothorax in 1 (6.7%), and wound dehiscence in 2 (13.3%). The 30-day mortality was 12.8%. The quality of life as assessed by Karnofsky performance status within 6–12 months after discharge in 32 children was 100 and in two patients (90). Conclusion: The most common indication and complication following thoracotomy at our institution was congenital anomalies in 25 (64.1%) patients (lung malformations, 35.9% and patent ductus arteriosus, 28.2%), and atelectasis, respectively. The 30-day mortality after thoracotomy was 12.8%.
背景:与成人相比,儿童开胸手术相对罕见。由于这个年龄段特殊的解剖学和生理学,这可能是非常具有挑战性的。该研究的目的是研究开胸手术的适应症、结果和并发症。方法:回顾性分析我院2011年1月至2020年12月全麻下行开胸手术的新生儿、婴儿和儿童病历。此外,我们还搜索了需要开胸手术的儿童胸部疾病;开胸术后的适应证、并发症及生活质量。患儿采用后外侧或外侧开胸术,保留背阔肌和/或前锯肌。收集的数据包括人口统计学、手术干预、重症监护病房住院时间、术后并发症和临床结果。结果:39例患者中,女性占多数20例(51.3%),其中先天性畸形25例(64.1%)为开胸手术最常见的适应症(肺畸形占35.9%,动脉导管未闭占28.2%),其次为异物吸入(20.21%)。术后并发症15例(38.5%),其中肺不张3例(20%),乳糜胸1例(6.7%),伤口裂开2例(13.3%)。30天死亡率为12.8%。32例儿童出院后6-12个月Karnofsky表现状态生活质量为100,2例患者为90。结论:我院开胸术后最常见的指征和并发症为先天性畸形25例(64.1%)(肺畸形35.9%,动脉导管未闭28.2%)和肺不张。开胸术后30天死亡率为12.8%。
{"title":"Thoracotomy in children: A decade review of indications and outcomes","authors":"E. Ogunleye, O. Olusoji, O. Adekola","doi":"10.4103/jcls.jcls_67_22","DOIUrl":"https://doi.org/10.4103/jcls.jcls_67_22","url":null,"abstract":"Background: Thoracotomy in children is relatively rare compared to adults. It can be very challenging due to the peculiar anatomy and physiology in this age group. The objective of the study was to study the indications, outcomes, and complications following thoracotomy. Methods: This was a retrospective analysis of the medical charts of neonates, infants, and children who had undergone thoracotomy under general anesthesia from January 2011 to December 2020 at our institution. Furthermore, we searched for the childhood thoracic diseases necessitating thoracotomy; the indications and complications following thoracotomy, as well as, the quality of life following thoracotomy. The children had either posterolateral or lateral thoracotomy, which spared the latissimus dorsi and/or serratus anterior. Data collected included demographics, surgical intervention, duration of intensive care unit admission, postoperative complications, and clinical outcome. Results: Out of the 39 patients, a majority were female 20 (51.3%), the most common indication for thoracotomy was congenital anomalies in 25 (64.1%) patients (lung malformations, 35.9% and patent ductus arteriosus, 28.2%), followed by foreign body aspiration (20.21%). Postoperative complications were seen in 15 (38.5%), out of whom 3 (20%) had atelectasis, chylothorax in 1 (6.7%), and wound dehiscence in 2 (13.3%). The 30-day mortality was 12.8%. The quality of life as assessed by Karnofsky performance status within 6–12 months after discharge in 32 children was 100 and in two patients (90). Conclusion: The most common indication and complication following thoracotomy at our institution was congenital anomalies in 25 (64.1%) patients (lung malformations, 35.9% and patent ductus arteriosus, 28.2%), and atelectasis, respectively. The 30-day mortality after thoracotomy was 12.8%.","PeriodicalId":15490,"journal":{"name":"Journal of Clinical Sciences","volume":"205 1","pages":"41 - 45"},"PeriodicalIF":0.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80391581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Journal of Clinical Sciences
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