Soot Pollution and Pathological Implications

R. Okafor, E. Onosakponome, C. Nyenke, Chikadibia Fyneface Amadi
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Abstract

Carbon-based soot, a black particulate material, is produced when fossil fuels burn partially. Soot is seen as an unwelcome byproduct that results from the insufficient combustion of carbon-containing compounds. The environment is affected by the deposition of soot in water, air and soil. These environmental components serves as a means of exposure to man although, the effect of water and soil exposure are poorly studied. This reviewed has also shown that three pathological conditions may occur as a result of soot exposure; they include- respiratory disorder, cardiovascular disease and cancer. Poly aromatic hydrocarbon (PAH) was reported as carcinogenic substance in soot that causes cancer. Direct contact-mediated lung cell failure and immune response involvement that results in cellular proliferation and fibrosis have been proposed as the mechanisms underlying respiratory illness. Inflammation of myocardiac tissues was considered the pathogenesis of cardiovascular disease in soot exposure individuals. Treatment options were based on the mechanism of soot pathology. Based on existing literatures, this review has demonstrated that soot polluted environment can lead to cancer, cardiovascular disease and respiratory disorder.
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烟尘污染及其病理意义
碳基烟尘是一种黑色颗粒物质,是化石燃料部分燃烧时产生的。煤烟被视为不受欢迎的副产品,是含碳化合物燃烧不足的结果。环境受到水、空气和土壤中烟灰沉积的影响。这些环境成分作为暴露于人类的一种手段,尽管对水和土壤暴露的影响研究甚少。这篇综述还表明,三种病理条件可能发生作为烟灰暴露的结果;它们包括呼吸系统疾病、心血管疾病和癌症。多环芳烃(PAH)是煤烟中的致癌物。直接接触介导的肺细胞衰竭和免疫反应参与导致细胞增殖和纤维化被认为是呼吸系统疾病的潜在机制。心肌组织炎症被认为是煤烟暴露个体心血管疾病的发病机制。根据烟灰病理机制选择治疗方案。在现有文献的基础上,本文综述了煤烟污染环境可导致癌症、心血管疾病和呼吸系统疾病。
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