Effect of Chronic Nasal Obstruction on Pulmonary Function

A. Saxena, Abhinav K. Srivastava, Chander Mohan, Amit Kumar
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引用次数: 2

Abstract

Introduction: Upper and lower respiratory diseases are closely related which has been well documented in literature. Even though a relationship between upper and lower airway disease has been described, altered pulmonary function in patients with upper airway diseases is still not fully understood. The present study was conducted to assess the effect of chronic nasal obstruction on pulmonary function and to compare the pulmonary function in same patients after surgical relief of nasal obstruction. Material and methods: The present study was carried out in the Department of ENT and Head and Neck Surgery and Department of Respiratory Medicine, Rohilkhand Medical College and Hospital, Bareilly between November 2017 to October 2018. 56 patients with chronic nasal obstruction due to either deviated nasal septum or chronic rhinosinusitis with or without nasal polyp underwent pulmonary function testing pre and post-operatively at 6 weeks and results were compared. Results: The most common age group affected was less than thirty years accounting for more than 50%. Mean age of total sample size was 24.2 ± 6.98 years. Thirty three (58.9%) patients were males while 23(41.07%) patients were females. Out of 56 subjects, 34(60.71%) patients underwent septoplasty, while 22(39.28%) patients underwent functional endoscopic sinus surgery. Clinically and statistically significant improvement in FEV1 and FVC was observed irrespective of age, gender or duration of obstruction. Conclusion: Patients with bilateral nasal obstruction had worse pulmonary function initially and more significant improvement after surgery, suggesting an association of bilateral obstruction with bad prognosis.
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慢性鼻塞对肺功能的影响
上呼吸道疾病与下呼吸道疾病密切相关,文献记载较多。尽管上下气道疾病之间的关系已被描述,但上气道疾病患者的肺功能改变仍未完全了解。本研究旨在评估慢性鼻塞对肺功能的影响,并比较相同患者手术解除鼻塞后肺功能的变化。材料与方法:本研究于2017年11月至2018年10月在巴雷利罗希尔坎德邦医学院耳鼻喉科、头颈外科和呼吸内科进行。对56例因鼻中隔偏曲或慢性鼻窦炎(伴或不伴鼻息肉)引起的慢性鼻塞患者在手术前和术后6周进行肺功能检查,并对结果进行比较。结果:30岁以下年龄组最常见,占50%以上。总样本量平均年龄为24.2±6.98岁。男性33例(58.9%),女性23例(41.07%)。56例患者中,34例(60.71%)患者行鼻中隔成形术,22例(39.28%)患者行功能性内窥镜鼻窦手术。无论年龄、性别或梗阻持续时间如何,FEV1和FVC在临床和统计学上均有显著改善。结论:双侧鼻塞患者初始肺功能较差,术后改善更明显,提示双侧鼻塞与预后不良有关。
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