Die gevaar van wye verspreiping van weerstandbiedendheid teen wurmmiddels deur veldramprestasietoetssentra

J. V. Wyk, P. V. Schalkwyk, Gareth F. Bath, H. M. Gerber, Regina M.R. Alves
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引用次数: 2

Abstract

A veld ram perfonnan~e testing unit consists of an association of stud or commercial ram breeders, who compare the performance of selected rams under field conditions on common pastures. The best perfonners are subsequently auctioned at public sales. To date, at least 10 Merino veld ram clubs have been established in various centres in South Africa. A strain of Haemonchus contortus, which was isolated from the pastures of one of these performance testing units, was found to be resistant to ivermectin, oxfendazo1e and rafoxanide. Closantel, levamisole and disophenol were more than 99% effective. The wide dispersal of the rams after testing, constitutes a potential danger for dissemination of helminths with resistant genes. Precautionary methods should include careful routine monitoring of drug susceptibility on the communal pastures, on the farms of individual members and thorough deworming of rams before they leave the testing unit. The prevention and control of resistance in such testing units are discussed, but it is emphasised that this is difficult, particularly if the worm strains on the communal grazing have become resistant to some of the anthelmintic groups.
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草原公羊性能测试单位由种马或商业公羊育种者协会组成,他们在普通牧场的野外条件下比较选定公羊的性能。表现最好的人随后会被公开拍卖。迄今为止,在南非的各个中心至少建立了10个美利奴草原公羊俱乐部。从这些性能测试单位之一的牧场中分离出的一株弯曲血蜱被发现对伊维菌素、奥芬达唑和拉福昔尼具有耐药性。Closantel、左旋咪唑和二酚的有效率超过99%。经检测,公羊的广泛分布构成了具有抗性基因的蠕虫传播的潜在危险。预防方法应包括对公共牧场和个体成员农场的药物敏感性进行仔细的常规监测,并在公羊离开测试单位之前对其进行彻底的驱虫。讨论了在这些测试单位中预防和控制耐药性,但强调这是困难的,特别是如果公共放牧的蠕虫菌株已经对某些驱虫群产生抗性。
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