General Anaesthesia for Cesarean Section in a Parturient with Long QT Syndrome: A Case Report and a Review of Literature

N. Kayacan, B. Karsli, U. Ince
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Abstract

Long QT syndrome patients are at high risk of developing ventricular arrhythmia and cardiac arrest, so that the anesthetic technique used for these patients must avoid anything that will induce an arrhythmia such as tachycardia, hypotension or increased catecholamine release by pain or stress. A 28 -yr-old woman was scheduled for an elective, repeat cesarean section at 36 weeks gestation. She was diagnosed long QT syndrome at age 22 and an automatic implantable cardiac defibrillator (AICD) was implanted. During her pregnancy, parturient was hospitalized at 35 weeks gestation because of fetal bradycardia and obstetrician scheduled cesarean section at 36 weeks gestation. Before induction of anaesthesia, esmolol 200mcg.kg.min -1 was started for prevention of ventricular dysrhythmia during laryngoscopy and tracheal intubation. After preoxygenation, anaesthesia was induced with fentanyl 100mcg, propofol 200mg, rocuronium 100 mg and trachea was intubated at 45 seconds. Esmolol infusion rate was reduced gradually to parturient’s Case Study Kayacan et al.; BJPR, 15(2): 1-7, 2017; Article no.BJPR.31699 2 haemodynamic parameters during surgery and was stopped at end of the surgery. At 4 minutes of the surgery, fetus was deliveried but there is no heart rate and breathing of baby. Following cardiac compression for 45 seconds, heart rate and breathing of baby returned. Anaesthesia was maintained with 1 MAC sevoflurane and 100 mcg fentanyl. Parturient’s blood pressure and heart rate remained within normal limits during surgery. Consequently, if parturient does not accept regional anaesthesia, in case of an emergency cesarean section, general anaesthesia can be safely used with optimized preoperative evaluation, close monitoring and carefully anaesthetic management.
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长QT综合征剖宫产术的全身麻醉:1例报告及文献复习
长QT综合征患者发生室性心律失常和心脏骤停的风险很高,因此用于这些患者的麻醉技术必须避免任何可能诱发心律失常的因素,如心动过速、低血压或因疼痛或压力而增加儿茶酚胺释放。一位28岁的女性在妊娠36周时被安排了一次选择性的重复剖宫产手术。她在22岁时被诊断为长QT综合征,并植入了自动植入式心脏除颤器(AICD)。在怀孕期间,由于胎儿心动过缓,孕妇在妊娠35周住院,产科医生在妊娠36周安排剖宫产。麻醉诱导前,艾司洛尔200mg .kg。Min -1用于预防喉镜检查和气管插管时室性心律失常。预充氧后,芬太尼100mcg、异丙酚200mg、罗库溴铵100mg诱导麻醉,45秒插管。艾司洛尔输注速率逐渐降低至患儿的病例研究Kayacan等;生物工程学报,15(2):1-7,2017;文章no.BJPR。31699 2术中血流动力学参数,并在手术结束时停止。手术4分钟,胎儿娩出,但胎儿无心跳和呼吸。心脏按压45秒后,婴儿心率和呼吸恢复正常。麻醉维持在七氟醚1mac和芬太尼100mcg。手术中,产妇的血压和心率保持在正常范围内。因此,如果产妇不接受区域麻醉,在紧急剖宫产的情况下,可以在优化术前评估、密切监测和仔细麻醉管理的情况下安全使用全身麻醉。
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