Characterization of gap junctions by electrophysiological and electronmicroscopical methods

D. Hülser, D. Paschke, F. Brümmer, R. Eckert
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引用次数: 1

Abstract

Gap junctions are ubiquitous in the animal kingdom from mesozoa to vertebrates. They must be discriminated from desmosomes which anchor cells together to form structural or functional units as well as from tight junctions which seal membranes of epithelial cells to each other so that the paracellular path becomes impermeable to molecules and a polarity of apical and basolateral surface is maintained.
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电生理和电子显微镜方法表征间隙连接
从中生代动物到脊椎动物,缝隙连接无处不在。它们必须与桥粒区分开来,桥粒将细胞固定在一起形成结构或功能单位,也必须与紧密连接区分开来,桥粒将上皮细胞的膜相互封闭,从而使细胞旁通路变得不被分子渗透,并维持细胞顶端和底外侧表面的极性。
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