Optical resolution and biological activities of S-23121, a new cereal herbicide

Abstract

trolling many broadleaved weeds.1} Like Nphenylimide herbicide S-23142, in which the l-methyl-2-propynyl of S-23121 is substituted by 2-propynyl, S-23121 induces an abnormal accumulation of protoporphyrin IX, leading to lipid peroxydation.1} S-23121, having a chiral center at C-l in its chemical structure, is an optically active compound. Antipodes of bioactive chiral molecules are often thought to show quite different biological activity. It is, therefore, of great interest to know whether both enantiomers of S-23121 show similar