Mechanistic Insight from a Volume Profile for Electron Transfer Between Promethazine and Hexaaquairon(III)

Abstract

Promethazine (dimethyl-(2-phenothiazin-10-ylpropyl)-amine) is one of a series of Nalkylphenothiazines that modify the physiological action of neurotransmission receptors. They are therefore used as medicine in a variety of pharmacological therapies related to a reduction of the neurotransmission effects.1 Other interesting features of the phenothiazine class of drugs include their ability to undergo one electron-transfer reactions and to form charge-transfer complexes with various Inorganic Reaction Mechanisims, Vol. 6, pp. 1-8 © 2006 Old City Publishing, Inc. Reprints available directly from the publisher Published by license under the OCP Science imprint, Photocopying permitted by license only a member of the Old City Publishing Group.