Lifestyle potential against recurrent intraoral herpes recurrence rate: a case series

A. Megawati, W. Hidayat
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Abstract

Introduction: Herpes Simplex Virus type 1 (HSV-1) is the virus that most often infects the oral cavity. HSV-1 in the latent phase migrates to the trigeminal ganglion after primary infection and can reactivate to cause recurrent intraoral herpes (RIH). The recurrence of RIH is multifactorial and triggered by decreased immunity, fatigue, hypersensitivity, stress, and ultraviolet. Case: Three male patients came to the Oral Disease Clinic with ulcers in the oral cavity. The patients experienced prodromal symptoms and the characteristic features of RIH were multiple rounded ulcers spreading and surrounded by erythematous areas. Anti-HSV-1 IgG examination showed reactive results. Management: The therapy was acyclovir and trigger factor modifica-tion. The oral lesions of all patients recovered after therapy and there were no new lesions. Conclusion: Lifestyle and habits have a high potential to be a triggering factor for RIH recurrence, so comprehensive treatment is needed to prevent recurrence.
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生活方式对口腔内疱疹复发率的潜在影响:一个病例系列
简介:1型单纯疱疹病毒(HSV-1)是最常感染口腔的病毒。潜伏期的HSV-1在初次感染后迁移到三叉神经节,并可重新激活引起复发性口腔内疱疹(RIH)。RIH的复发是多因素的,可由免疫力下降、疲劳、过敏、压力和紫外线引起。病例:3例男性患者因口腔溃疡来到口腔疾病门诊就诊。患者出现前驱症状,RIH的特征是多个圆形溃疡扩散并被红斑区包围。抗hsv -1 IgG检测呈反应性。处理:治疗是阿昔洛韦和触发因子修饰。所有患者治疗后口腔病变均恢复正常,无新发病变。结论:生活方式和生活习惯极有可能成为RIH复发的触发因素,需要综合治疗预防复发。
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