Antibiotics for UTI in children . . . and other stories

IF 10 BMJ medicine Pub Date : 2023-08-17 DOI:10.1136/bmj.p1830
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Abstract

How long a course of antibiotics is needed for children with urinary tract infections? A randomised trial failed to reach a definite answer. Among 650 children aged 2 months to 10 years who showed clinical improvement after fivedaysof antimicrobials, half were allocated to another five days of antimicrobials and the other half to five days of placebo. Recurrence of symptomswasmore common in those receiving placebo, but the absolute rate of treatment failure was low (JAMA Pediatr doi:10.1001/jamapediatrics.2023.1979).
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儿童尿路感染的抗生素…还有其他的故事
儿童尿路感染需要多长时间的抗生素疗程?一项随机试验未能得出明确的答案。在650名2个月至10岁的儿童中,他们在服用抗菌素5天后表现出临床改善,其中一半被分配到另外5天的抗菌素,另一半被分配到5天的安慰剂。在接受安慰剂治疗的患者中,症状复发更为常见,但绝对治疗失败率较低(JAMA pediatrics doi:10.1001/ jamapediatics .2023.1979)。
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