The effect of lifestyle change on autonomic nervous system dysfunction in patients with metabolic syndrome

A. Birant, G. Kozdağ, D. Ural, A. Ağır
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Abstract

Study Design: A prospective clinical cohort study. Objective: In this study, it was aimed to examine the effects of metabolic syndrome, which affects many organs, on the autonomic nervous system and to observe the changes after treatment. Materials and Methods: Heart rate variability values of 101 metabolic syndrome patients who were treated at the Kocaeli University Cardiology Outpatient Clinic included in the study. All patients were offered lifestyle change suggestions in addition to their medical treatments. At the end of three months, the heart rate variability parameters of the patients were re-evaluated. Results: Heart rate variability values were found to be significantly lower in metabolic syndrome patients compared to the control group. It was observed that the heart rate variability values improved significantly in half of the patients who applied the given treatment with lifestyle changes. A decrease in heart rate change parameters was found in the group that did not implement lifestyle changes compared to the beginning of the study. Conclusions: Autonomic nervous system functions evaluated by heart rate variability decreased in patients with metabolic syndrome, and the treatment and lifestyle changes had a positive effect on these parameters.
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生活方式改变对代谢综合征患者自主神经系统功能障碍的影响
研究设计:前瞻性临床队列研究。目的:本研究旨在探讨影响多脏器的代谢综合征对自主神经系统的影响,并观察治疗后的变化。材料和方法:纳入研究的101例在Kocaeli大学心脏病学门诊接受治疗的代谢综合征患者的心率变异性值。所有患者除了接受药物治疗外,还接受了改变生活方式的建议。3个月后,重新评估患者心率变异性参数。结果:与对照组相比,代谢综合征患者的心率变异性值明显降低。我们观察到,在接受了改变生活方式的治疗的患者中,有一半的患者心率变异性值得到了显著改善。与研究开始时相比,没有改变生活方式的那一组的心率变化参数有所下降。结论:代谢综合征患者心率变异性评价的自主神经系统功能下降,治疗和生活方式的改变对这些参数有积极影响。
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