Prevalence of Malaria among Febrile Patients Attending Government Hospitals in Ondo State, South-West Nigeria

F. Omoya, K. Ajayi
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引用次数: 1

Abstract

The use of malaria infection prevalence among febrile patients is a valuable epidemiological surveillance tool. In this study, a cross sectional study was conducted among febrile patients in selected government Hospitals in Ondo State for malaria prevalence. Plasmodium falciparum is the only encountered malaria parasite with prevalence values of 82.72% (426/515) and 80.19% (413/515) obtained using microscopy and RDTs respectively. The prevalence of malaria among the males (86.59%) was higher than the females (80.65%), all age groups in this study were vulnerable with highest infection rate of 89.66% among age group 11-20 years. The parasites densities ranged between 209 and 22310 parasites/μL with a mean parasitaemia of 5522.17±183.30 parasites/μL. The prevalence of malaria among the febrile participants that have used antimalarial drug before visiting the hospital is 82.94% (389/469) with the mean parasitaemia of 4615.21±188.14 parasites/μL while those that have used herbs before visiting the hospital had malaria prevalence of 85.03% (142/167) with the mean parasitaemia of 4913.81±330.20 parasites/μL. There was high prevalence of malaria among febrile patients. This finding will help improve the diagnosis and treatment of other febrile (non-malaria) infections, limit antimalarial usage to only malaria parasite-based test true positives and serve as a guide to combat malaria drug resistance in the study area.
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尼日利亚西南部翁多州政府医院发热病人疟疾流行情况
使用发热病人疟疾感染流行率是一种有价值的流行病学监测工具。在这项研究中,对翁多州选定的政府医院的发热病人进行了疟疾流行情况的横断面研究。恶性疟原虫(Plasmodium falciparum)是唯一的疟疾寄生虫,镜检和RDTs的患病率分别为82.72%(426/515)和80.19%(413/515)。男性疟疾患病率(86.59%)高于女性(80.65%),各年龄组均为易感人群,11 ~ 20岁年龄组感染率最高,为89.66%。寄生虫密度在209 ~ 22310只/μL之间,平均寄生量为5522.17±183.30只/μL。就诊前使用过抗疟药物的发热组疟疾患病率为82.94%(389/469),平均寄生虫量为4615.21±188.14只/μL;就诊前使用过中草药的发热组疟疾患病率为85.03%(142/167),平均寄生虫量为4913.81±330.20只/μL。发热病人中疟疾流行率高。这一发现将有助于改善其他发热性(非疟疾)感染的诊断和治疗,将抗疟疾药物的使用限制在仅基于疟疾寄生虫的检测真阳性,并作为在该研究地区抗击疟疾耐药性的指南。
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