Research Progress Based on Serious Complication of Stroke in Patients with Chronic Kidney Disease

Yunchuan Tian, Qingyang Zhu, Yonglian Tang, Rongkun Li, Jiang Xiao
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Abstract

Patients with chronic renal insufficiency (CKD) in the uremic stage can suffer various degrees of damage to various organ systems throughout the body, with the nervous system being common and severe. Chronic kidney disease (CKD) complicated with stroke has a high incidence and poor prognosis, which brings a heavy burden to patients and society. Understanding the risk factors of uremic patients complicated with stroke and taking preventive measures as soon as possible is of great significance for controlling the progress of the disease. The risk factors of uremic patients complicated with stroke are complex and diverse. Traditional risk factors include hypertension, diabetes, atrial fibrillation, dyslipidemia, etc. Non traditional risk factors such as genetic susceptibility, uremia, anemia, mineral and bone abnormalities can also promote the occurrence of stroke. In addition, dialysis related risk factors such as insufficient cerebral perfusion, increased arterial stiffness, and increased blood pressure variability can also cause stroke. Therefore, it is important to identify the risk factors of stroke in uremic patients as early as possible and take targeted preventive measures.
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慢性肾脏疾病患者卒中严重并发症的研究进展
慢性肾功能不全(CKD)患者在尿毒症期可对全身各器官系统造成不同程度的损害,以神经系统为常见且严重。慢性肾脏疾病(CKD)合并脑卒中发病率高,预后差,给患者和社会带来了沉重的负担。了解尿毒症患者并发脑卒中的危险因素,尽早采取预防措施,对控制病情发展具有重要意义。尿毒症患者并发脑卒中的危险因素复杂多样。传统的危险因素包括高血压、糖尿病、心房颤动、血脂异常等。遗传易感性、尿毒症、贫血、矿物质和骨骼异常等非传统危险因素也可促进中风的发生。此外,与透析相关的危险因素,如脑灌注不足、动脉硬化增加和血压变异性增加也可引起中风。因此,尽早识别尿毒症患者发生脑卒中的危险因素,采取有针对性的预防措施十分重要。
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