Bone resorption caused by systemic sclerosis

H. Yin, Liangji Lu
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Abstract

Hanlin Yin, Liangjing Lu This woman in her 60s presented with a history of a progressively receding chin over several years (fig 1). She also had a 15 year history of diffuse cutaneous systemic sclerosis. On examination, her nose appeared pinched and she had circumoral furrows, thin lips, microstomia, and a retracted chin. Facial computed tomography showed calcium deposits in the soft tissue surrounding the temporomandibular joint and bone resorption of the mandible. Bone resorption is thought to occur in systemic sclerosis as a result of tissue ischaemia; typically the fingers are affected.1 2 Mandibular resorption can occur in 8% of patients with systemic sclerosis and is usually asymptomatic.3 In severe cases, surgical reconstruction can correct facial structural anomalies.
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系统性硬化症引起的骨吸收
患者60多岁,下颌渐进式后退数年(图1),弥漫性皮肤系统性硬化症病史15年。检查时,她的鼻子出现挤压,周围有皱纹,嘴唇薄,小口,下巴后缩。面部计算机断层扫描显示颞下颌关节周围软组织钙沉积和下颌骨骨吸收。骨吸收被认为发生在系统性硬化症中,是组织缺血的结果;通常手指会受到影响。8%的系统性硬化症患者可发生下颌骨吸收,且通常无症状在严重的情况下,手术重建可以纠正面部结构异常。
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