Sleep Disorders and Chronic Constipation: Relation to Other Co-morbidities?

S. Szeinbach, R. Rodriguez-Monguio, R. Baran, P. Williams
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引用次数: 1

Abstract

Sleep disorders are common complaints and frequently associated with a number of disease states. Although the link between sleep disorders, respiratory diseases, and other co-morbid conditions experienced by patients has been investigated, the link between sleep disorders and chronic constipation is relatively unexplored. Given the widespread oc- currence of sleep disorders, it is important to evaluate how sleep disorders relate to respiratory diseases and other co- morbid disease states in participants with chronic constipation. Thus, the purpose of this study was to identify co-morbid conditions that were significant predictors for chronic constipation participants with and without sleep disorders. Of the 311 participants with a confirmed diagnosis of chronic constipation, 84% of the sample was female with 52% having sleep disorders, approximately two-thirds reported allergies, and 30% or less reported chronic sinusitis, chronic bronchitis, asthma, and chronic obstructive pulmonary disease (COPD). Results from logistic regression analysis revealed significant odds ratios for sleep disorders and allergies (OR 2.4; p = 0.001), asthma (OR 2.0; p = 0.01), chronic bronchitis (OR 2.2; p = 0.014), COPD (OR 4.0; p < 0.001), sinusitis (OR 2.0; p = 0.008), and for other co-morbid conditions. Perceptions of overall health were significantly worse (p < 0.001) for chronic constipation participants with certain co-morbid conditions including sleep disorders, respiratory diseases, and disease states producing pain. Co-morbid conditions may influence in- formation provided by patients when discussing family history, diagnosing, discussing pharmacotherapy, and monitoring patient-reported outcomes. Co-morbid conditions should be considered by physicians and specialists during patient as- sessment and evaluation. Keyword: Allergic disease, upper respiratory, insomnia, Constipation, Co-morbid conditions, diagnosis, clinical evaluation.
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睡眠障碍和慢性便秘:与其他合并症的关系?
睡眠障碍是常见的主诉,通常与许多疾病状态有关。虽然已经研究了睡眠障碍、呼吸系统疾病和患者经历的其他共病之间的联系,但睡眠障碍和慢性便秘之间的联系还相对未被探索。鉴于睡眠障碍的广泛发生,评估睡眠障碍与慢性便秘患者的呼吸系统疾病和其他共病状态的关系是很重要的。因此,本研究的目的是确定伴随病是有或无睡眠障碍的慢性便秘参与者的重要预测因素。在确诊为慢性便秘的311名参与者中,84%的样本是女性,52%有睡眠障碍,大约三分之二的人报告过敏,30%或更少的人报告慢性鼻窦炎、慢性支气管炎、哮喘和慢性阻塞性肺病(COPD)。logistic回归分析结果显示,睡眠障碍和过敏的比值比显著(OR 2.4;p = 0.001),哮喘(OR 2.0;p = 0.01),慢性支气管炎(OR 2.2;p = 0.014), COPD (OR 4.0;p < 0.001),鼻窦炎(OR 2.0;P = 0.008),以及其他合并症。慢性便秘参与者对整体健康状况的感知明显更差(p < 0.001),其中包括睡眠障碍、呼吸系统疾病和产生疼痛的疾病状态。当讨论家族史、诊断、讨论药物治疗和监测患者报告的结果时,合并症可能影响患者提供的信息。医生和专家在对患者进行评估时应考虑合并症。关键词:变应性疾病,上呼吸道,失眠,便秘,合并症,诊断,临床评价
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