Endometriosis and Adenomyosis Effect on IVF Outcome

Hend Allaw, A. B. Zetoune, M. Alhalabi
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Abstract

Endometriosis is a very common debilitating disease that occurs in 6 to 10 percent of the general female population; in women with pain, infertility, or both, the frequency is 35–50%. Endometriosis is one of the most important causes of infertility. Our objective is to evaluate the effect of endometriosis and adenomyosis on IVF outcome (ongoing pregnancy). 65 women underwent In Vitro Fertilization (IVF) and embryos transfer who had endometriosis with or without adenomyosis were recruited in this retrospective study, resulting in 53.8% had a successful IVF attempt (get pregnant). The highest success rate of IVF was in women who were in mild of endometriosis and IVF failure rate was increased mainly in women who were in severe endometriosis. So, the presence of adenomyosis affects IVF outcome and decreases the rate of implantation.
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子宫内膜异位症和子宫腺肌症对体外受精结果的影响
子宫内膜异位症是一种非常常见的使人衰弱的疾病,发生在普通女性人口的6%到10%;在疼痛、不孕或两者兼而有之的女性中,发病率为35-50%。子宫内膜异位症是导致不孕的最重要原因之一。我们的目的是评估子宫内膜异位症和子宫腺肌症对体外受精结果(持续妊娠)的影响。本回顾性研究招募了65例伴有或不伴有子宫腺肌症的子宫内膜异位症患者进行体外受精(IVF)和胚胎移植,结果53.8%的患者体外受精(IVF)成功(怀孕)。轻度子宫内膜异位症患者体外受精成功率最高,重度子宫内膜异位症患者体外受精失败率主要增高。因此,子宫腺肌病的存在会影响IVF的结果并降低着床率。
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