Liver Metastases From Noncolorectal Malignancies (Neuroendocrine Tumor, Sarcoma, Melanoma, Breast)

E. Alexander, M. Soulen
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引用次数: 6

Abstract

AbstractPatients with noncolorectal hepatic metastases often face limited treatment options and a dismal prognosis. Over the last decade, the advent of targeted immunotherapies has transformed the treatment of certain metastatic cancers, such as sarcoma and melanoma; however, these patients eventually develop resistance. Metastatic sarcoma, melanoma, and breast and neuroendocrine tumors are notoriously treatment resistant once they have metastasized to the liver. For these cancers, minimally invasive transarterial and ablation therapies have emerged as safe, palliative therapies that can provide symptom control and even prolong survival.
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非结直肠恶性肿瘤(神经内分泌肿瘤、肉瘤、黑色素瘤、乳腺)肝转移
摘要非结直肠肝转移患者通常面临有限的治疗选择和惨淡的预后。在过去的十年中,靶向免疫疗法的出现改变了某些转移性癌症的治疗方法,如肉瘤和黑色素瘤;然而,这些患者最终会产生耐药性。转移性肉瘤、黑色素瘤、乳腺和神经内分泌肿瘤一旦转移到肝脏,就很难治疗。对于这些癌症,微创经动脉和消融治疗已经成为安全的姑息性治疗,可以提供症状控制,甚至延长生存期。
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