Pathogenic bacteria of diabetic-associated infections and their pathogenesis

S. S. Khazaal, M. Talha, Anmar A. Raheem
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引用次数: 1

Abstract

ISSN The diabetic patients have tendencies to develop infections in presence of hyperglycemia makes mucosal epithelial more susceptible to infections. Diabetic mellitus causes a sever deregulation of immune response in a healthy human body. The suppressed production of immune pepetides and altered immune, susceptibility to infections are much higher in immunosuppressed patients with diabetes mellitus. The human host and microorganisms normally exist in a balanced relationship. Infection occurs when pathogens are able to resist host’s immune system and subsequently invade systemic host responses. The reasons why infections do not recover are related to local factors associated with the infections and also with comorbidities such as diabetes. In this review, we discuss the influence of diabetes in bacterial infection and their mechanism emphasizing their role in bacterial pathogensis. Copyright 2020 Wolters Kluwer Health, Inc. All rights reserved.
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糖尿病相关感染的致病菌及其发病机制
糖尿病患者有发生感染的倾向,高血糖使粘膜上皮更容易感染。糖尿病引起健康人体免疫反应的严重失调。免疫抑制的糖尿病患者免疫肽的产生受到抑制,对感染的免疫易感性发生改变。人类宿主和微生物通常以一种平衡的关系存在。当病原体能够抵抗宿主的免疫系统并随后侵入宿主的全身反应时,就会发生感染。感染不能恢复的原因与感染相关的局部因素以及糖尿病等合并症有关。本文就糖尿病对细菌感染的影响及其机制作一综述,重点介绍糖尿病在细菌致病中的作用。威科集团版权所有版权所有。
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来源期刊
Reviews in Medical Microbiology
Reviews in Medical Microbiology 生物-微生物学
CiteScore
1.80
自引率
0.00%
发文量
0
审稿时长
>12 weeks
期刊介绍: Reviews in Medical Microbiology is a quarterly review journal which provides a balanced coverage of the whole field of medical microbiology. The Journal publishes state-of-the art reviews, mini-reviews, case presentations and original research from on-going research of the latest developments and techniques in medical microbiology, virology, mycology, parasitology, clinical microbiology, and hospital infection.​ In addition, PhD-Review - a platform for young researchers, and biographical Bio-Sketch articles are also considered. Reviews are concise, authoritative, and readable synthesis of the latest information on its subject, and references are limited to the fifty key sources for full reviews and twenty for mini-reviews. Reviews in Medical Microbiology is the perfect way for both qualified and trainee microbiologists, and researchers and clinicians with an interest in microbiology, to stay fully informed of the latest developments in medical microbiology. The journal is a valuable resource for educational and teaching purposes.
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