F. Cecchi, T. Vezzosi, G. Branchi, G. Barsotti, F. Macchioni
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引用次数: 1
Abstract
ABSTRACT The aims of this study were to analyze the inbreeding (F) in a colony of Labrador Retriever (LR) guide dogs using information from pedigrees and to verify its role in increasing the occurrence of various genetic diseases (hereditary eye diseases, heart problems, hip and elbow dysplasia). Pedigree data and medical reports were collected for 40 LR bred for training by the National Guide Dog School (NGDS) of Scandicci (Italy). The chi-square independence test for two effects was performed: inbreeding level and disorders occurrence. The main disorder highlighted was elbow dysplasia (ED) (17.5%, 95% CI 8.40–26.60%). The number of inbred animals was 15 (37.5%) with an average inbreeding coefficient of 0.017. The association between inbreeding levels and disorders was not significant as there was a similar percentage of inbred animals and non-inbred animals among the sick. The results highlight that disease occurrence does not depend on low inbreeding levels.
摘要本研究的目的是利用家系信息分析拉布拉多猎犬(LR)导盲犬群体的近亲繁殖(F)，并验证其在增加各种遗传疾病(遗传性眼病、心脏病、髋部和肘部发育不良)发生率中的作用。收集了意大利斯坎迪奇国家导盲犬学校(NGDS)训练的40只LR的血统数据和医学报告。对近交水平和疾病发生两种效应进行卡方独立检验。突出的主要疾病是肘关节发育不良(ED) (17.5%， 95% CI 8.40-26.60%)。自交系数为15头(37.5%)，平均近交系系数为0.017。近亲繁殖水平与疾病之间的关系并不显著，因为患病的近亲繁殖动物和非近亲繁殖动物的比例相似。结果强调，疾病的发生并不取决于低近交水平。
期刊介绍：
Acta Agriculturæ Scandinavica, Section A – Animal Science publishes results of original research in animal science and their applications related to the following topics:
-Animal breeding and genetics
-Molecular genetics
-Animal physiology and reproduction
-Nutrition and feeding
-Animal behaviour and welfare
-General animal husbandry and systems of production, including economic and technical aspects
-Hygiene and quality of animal products
In addition to original articles, covering basic as well as applied subjects, the journal features review articles and short communications.
Acta Agriculturæ Scandinavica, Section A – Animal Science forms part of a trilogy of titles published on behalf of the Nordic Association of Agricultural Scientists (NJF). The series also includes Section B - Soil & Plant Science and the recently launched Section C - Food Economics .
Acta Agriculturae Scandinavica A, B and C are available to purchase as a combined subscription. This provides access to all three journals in the series, and is available to institutional subscribers only. For full pricing information, please view the Taylor & Francis Journals Price List here.
Scientists in research, teaching and extension with specialised interest in animal science and production.
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