{"title":"Can Nanotechnology help Push the Limit for Early Cancer Diagnostics","authors":"M. Agrawal, Abhijit Biswas","doi":"10.15406/jnmr.2017.05.00100","DOIUrl":null,"url":null,"abstract":"J Nanomed Res 2017, 5(1): 00100 connected with it). Therefore, applications of these techniques are limited due to the lack of sufficient sensitivity to detect small numbers of malignant cells in the primary or even metastatic sites [1]. It is also difficult to detect specific cancer cell-surface markers, which are not only a target for cancer therapy but can also assist in the diagnosis and staging of cancer. Other challenges include inadequate drug concentrations reaching the tumor and the limited ability to monitor therapeutic responses thus leading to significant complications such as multidrug resistance due to poor drug delivery [1].","PeriodicalId":16465,"journal":{"name":"Journal of Nanomedicine Research","volume":"17 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2017-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Nanomedicine Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15406/jnmr.2017.05.00100","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
J Nanomed Res 2017, 5(1): 00100 connected with it). Therefore, applications of these techniques are limited due to the lack of sufficient sensitivity to detect small numbers of malignant cells in the primary or even metastatic sites [1]. It is also difficult to detect specific cancer cell-surface markers, which are not only a target for cancer therapy but can also assist in the diagnosis and staging of cancer. Other challenges include inadequate drug concentrations reaching the tumor and the limited ability to monitor therapeutic responses thus leading to significant complications such as multidrug resistance due to poor drug delivery [1].