{"title":"MODULATORY EFFECTS OF CHRONIC ETHANOL INGESTION ON HEPATOTOXICITY-RELATED PARAMETERS IN MALE RATS","authors":"O. Ighodaro, J. Omole","doi":"10.4314/ARI.V6I3.55981","DOIUrl":null,"url":null,"abstract":"5 g of ethanol (20% w/v) per kg body weight was administered to ten rats weighing between 166 – 170 grams daily for 28 days along side with normal feeds and water ad libitum. The administration of ethanol was done orally using oral catheter. A control group o ten rats was set up for a proper experimental evaluation. Analysis at the end of the adminstration showed tha ethanol in a dose of 5g/kg body weight significantly modulates (P Keywords: Rats, Ethanol, Oral administration, Catheter, Liver, Hepatotoxicity, Antioxidant enzyme","PeriodicalId":7872,"journal":{"name":"Animal Research International","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2010-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Animal Research International","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4314/ARI.V6I3.55981","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
5 g of ethanol (20% w/v) per kg body weight was administered to ten rats weighing between 166 – 170 grams daily for 28 days along side with normal feeds and water ad libitum. The administration of ethanol was done orally using oral catheter. A control group o ten rats was set up for a proper experimental evaluation. Analysis at the end of the adminstration showed tha ethanol in a dose of 5g/kg body weight significantly modulates (P Keywords: Rats, Ethanol, Oral administration, Catheter, Liver, Hepatotoxicity, Antioxidant enzyme
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