Sales of Brand-Name Products and Generic Competitors Before and After Market Entry of Product Line Extensions in Canada

H. Xue, Ho-lun Wong, Patrick Wong, T. Einarson
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引用次数: 1

Abstract

ABSTRACTWe examined the success of product line extensions (PLEs) in Canada by studying five selected drugs, three with generic competitors (ciprofloxacin, fenofibrate, paroxetine) and two without (clarithromycin, tolterodine). Third-party prescription claims from Canada were used to examine market behavior, which was analyzed using multiple regression and ARIMA. Consistent negative associations indicated high substitutability for all products and their generics. However, this was found only for PLEs with distinct advantages (e.g., increased bioavailability, fewer side effects). PLEs may recapture some market share lost to generics, but success is product-specific and likely depends on the extent of the PLE's therapeutic advantage over the originator.
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加拿大产品线扩展进入市场前后品牌产品和非专利竞争对手的销售情况
摘要本研究通过对5种药物进行研究,考察了在加拿大的产品线扩展是否成功,其中3种有仿制药竞争对手(环丙沙星、非诺贝特、帕罗西汀),2种无仿制药竞争对手(克拉霉素、托特罗定)。来自加拿大的第三方处方索赔用于检验市场行为,使用多元回归和ARIMA进行分析。一致的负相关表明所有产品及其仿制药具有高可替代性。然而,这仅发现于具有明显优势(例如,提高生物利用度,减少副作用)的ple。仿制药可能会重新夺回被仿制药夺去的部分市场份额,但成功与否取决于具体产品,可能取决于仿制药相对于原研药的治疗优势程度。
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