{"title":"Metabolic inhibitors as stimulating factors for citric acid production","authors":"Z. Nehad, M. Essam, A. Hába","doi":"10.5580/1946","DOIUrl":null,"url":null,"abstract":"The effect of some metabolic inhibitors on citric acid production by Aspergillus niger in cane molasses medium was investigated. Addition of 0.01-0.1 iodoacetic acid and sodium arsenate, 0.05 -1.0 sodium malonate, 0.01 sodium azide , 0.01-0.05 sodium fluoride , 0.1-1.0 EDTA stimulated citric acid production (5-49%), but not necessary total titratable acids. Higher concentrations 10mM of iodoacetic acid , sodium malonate and 0.5 mM sodium azide caused a complete inhibition of fungal growth. 0.2 mM of iodoacetic acid, sodium arsenate and sodium fluoride caused a remarkable inhibition of citric acid production. The implications of those preliminary functions was discussed.","PeriodicalId":22514,"journal":{"name":"The Internet journal of microbiology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Internet journal of microbiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5580/1946","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 4
Abstract
The effect of some metabolic inhibitors on citric acid production by Aspergillus niger in cane molasses medium was investigated. Addition of 0.01-0.1 iodoacetic acid and sodium arsenate, 0.05 -1.0 sodium malonate, 0.01 sodium azide , 0.01-0.05 sodium fluoride , 0.1-1.0 EDTA stimulated citric acid production (5-49%), but not necessary total titratable acids. Higher concentrations 10mM of iodoacetic acid , sodium malonate and 0.5 mM sodium azide caused a complete inhibition of fungal growth. 0.2 mM of iodoacetic acid, sodium arsenate and sodium fluoride caused a remarkable inhibition of citric acid production. The implications of those preliminary functions was discussed.
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